HsaEX0059826 @ hg19
Exon Skipping
Gene
ENSG00000188687 | SLC4A5
Description
solute carrier family 4, sodium bicarbonate cotransporter, member 5 [Source:HGNC Symbol;Acc:18168]
Coordinates
chr2:74458363-74460690:-
Coord C1 exon
chr2:74460529-74460690
Coord A exon
chr2:74459596-74459774
Coord C2 exon
chr2:74458363-74458435
Length
179 bp
Sequences
Splice sites
3' ss Seq
CCCCAACCCCGCTCCTGCAGAAG
3' ss Score
6.7
5' ss Seq
CAGGTAGGA
5' ss Score
9.79
Exon sequences
Seq C1 exon
CCAACGCGGCCTGACCGAGGCTGGTTCGTGGCCCCCTTTGGGAAGAACCCGTGGTGGGTATACCCAGCAAGCATCCTGCCCGCCCTGCTGGTGACCATCCTGATCTTCATGGACCAGCAGATCACTGCCGTCATTGTCAACCGGAAGGAGAACAAACTGAAG
Seq A exon
AAGGCTGCCGGCTACCATCTGGACCTGTTCTGGGTGGGCATCCTCATGGCTTTGTGCTCCTTTATGGGGCTCCCCTGGTACGTGGCTGCCACGGTCATCTCCATCGCCCACATCGACAGCCTCAAGATGGAGACAGAGACCAGTGCCCCTGGGGAGCAGCCCCAGTTTCTGGGAGTCAG
Seq C2 exon
GGAACAGAGAGTAACCGGCATCATCGTCTTCATCCTGACGGGAATCTCTGTCTTCCTGGCTCCCATCCTAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188687_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.007 A=0.007 C2=0.095
Domain overlap (PFAM):
C1:
PF0095516=HCO3_cotransp=FE(11.2=100)
A:
PF0086015=Xan_ur_permease=PU(1.7=1.7)
C2:
PF0086015=Xan_ur_permease=FE(41.4=100)
Other Inclusion Isoforms:
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTGACCGAGGCTGGTTCG
R:
CTTTAGGATGGGAGCCAGGAAG
Band lengths:
226-405
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)