HsaEX0059858 @ hg19
Exon Skipping
Gene
ENSG00000050438 | SLC4A8
Description
solute carrier family 4, sodium bicarbonate cotransporter, member 8 [Source:HGNC Symbol;Acc:11034]
Coordinates
chr12:51857398-51868231:+
Coord C1 exon
chr12:51857398-51857498
Coord A exon
chr12:51863398-51863572
Coord C2 exon
chr12:51868126-51868231
Length
175 bp
Sequences
Splice sites
3' ss Seq
TGTCTGTTGTGTTTCCACAGGCT
3' ss Score
11.89
5' ss Seq
ATAGTAAGG
5' ss Score
4.33
Exon sequences
Seq C1 exon
GAGAAAAGGAAAATGCCTGGAGTTCCAAATGGAAATGTTTGCCACATAGAACAGGAACCACATGGGGGTCACAGTGGGCCAGAACTTCAGCGCACTGGGCG
Seq A exon
GCTATTTGGGGGCTTGGTGCTGGACATCAAGCGGAAGGCCCCCTGGTACTGGAGCGACTACCGAGATGCACTCAGCTTACAGTGTTTGGCTTCCTTTCTGTTCCTGTACTGTGCCTGCATGTCACCTGTCATCACCTTTGGGGGACTGCTTGGAGAAGCCACTGAGGGACGCATA
Seq C2 exon
CTGCAGGTGTACTCTGCCAGAGAATCCAAACAATCACACCCTCCAGTACTGGAAGGACCACAACATCGTGACAGCAGAAGTCCACTGGGCTAACCTGACTGTCAGT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000050438_MULTIEX2-5/13=2-8
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.798 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0095516=HCO3_cotransp=PU(1.2=17.6)
A:
PF0095516=HCO3_cotransp=FE(11.3=100)
C2:
PF0095516=HCO3_cotransp=PD(19.3=79.3)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AAAGGAAAATGCCTGGAGTTCCA
R:
CTGACAGTCAGGTTAGCCCAG
Band lengths:
202-377
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)