HsaEX0064953 @ hg38
Exon Skipping
Gene
ENSG00000156299 | TIAM1
Description
T-cell lymphoma invasion and metastasis 1 [Source:HGNC Symbol;Acc:HGNC:11805]
Coordinates
chr21:31164962-31187087:-
Coord C1 exon
chr21:31187001-31187087
Coord A exon
chr21:31182421-31182645
Coord C2 exon
chr21:31164962-31165065
Length
225 bp
Sequences
Splice sites
3' ss Seq
TTTCCATCTTGCGTTGGCAGGCC
3' ss Score
8.37
5' ss Seq
CAGGTATGG
5' ss Score
9.99
Exon sequences
Seq C1 exon
GGTTTTCACTTTCTTCTGTGGAAGAAGATGGTATTCGAAGGCTGTACGTGAATAGTGTGAAGGAAACCGGTTTAGCTTCCAAGAAAG
Seq A exon
GCCTGAAAGCAGGAGATGAGATTCTTGAGATCAATAATCGTGCTGCTGACGCCCTGAACTCTTCTATGCTCAAAGATTTCCTCTCACAGCCCTCGCTGGGCCTCCTGGTGAGGACCTACCCCGAGCTGGAGGAAGGAGTGGAGCTGCTGGAAAGCCCGCCCCACCGAGTGGACGGCCCTGCCGACCTTGGCGAGAGCCCCCTCGCCTTTCTCACCAGCAACCCAG
Seq C2 exon
GGCACAGCCTTTGCAGCGAGCAGGGCAGCAGTGCTGAGACCGCTCCAGAGGAGACCGAGGGGCCAGACTTGGAATCCTCAGATGAGACTGATCACAGCAGCAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000156299-'68-54,'68-51,71-54
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.007 A=0.421 C2=1.000
Domain overlap (PFAM):
C1:
PF0219610=RBD=PD(18.9=46.7),PF0059519=PDZ=FE(35.8=100)
A:
PF0059519=PDZ=PD(45.7=48.7)
C2:
NO
Main Skipping Isoform:
ENST00000286827fB28057
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGTTTTCACTTTCTTCTGTGGAA
R:
TTGCTGCTGTGATCAGTCTCA
Band lengths:
190-415
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
- Pre-implantation embryo development