HsaEX0070263 @ hg38
Exon Skipping
Gene
ENSG00000160293 | VAV2
Description
vav guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:12658]
Coordinates
chr9:133768442-133770501:-
Coord C1 exon
chr9:133770378-133770501
Coord A exon
chr9:133769417-133769503
Coord C2 exon
chr9:133768442-133768596
Length
87 bp
Sequences
Splice sites
3' ss Seq
TCTCTCTCGCCTCTTTGCAGCTT
3' ss Score
10.46
5' ss Seq
CAGGTACCG
5' ss Score
10.05
Exon sequences
Seq C1 exon
GAGTTGGTGGAGTACTACCAGTGCCACTCACTGAAGGAGAGCTTCAAGCAGCTGGACACCACACTCAAGTACCCCTACAAGTCCCGGGAACGTTCGGCCTCCAGGGCCTCCAGCCGGTCCCCAG
Seq A exon
CTTCCTGTGCTTCCTACAACTTTTCTTTTCTCAGTCCTCAGGGCCTCAGCTTTGCTTCTCAGGGCCCCTCCGCTCCCTTCTGGTCAG
Seq C2 exon
TGTTCACGCCCCGCGTCATCGGCACAGCTGTGGCCAGGTATAACTTTGCCGCCCGAGATATGAGGGAGCTTTCGCTGCGGGAGGGTGACGTGGTGAGGATCTACAGCCGCATCGGCGGAGACCAGGGCTGGTGGAAGGGCGAGACCAACGGACGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160293_MULTIEX1-2/2=1-C2
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
Show PDB structure
Features
Disorder rate (Iupred):
C1=0.030 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0001719=SH2=PD(6.7=11.9)
A:
NO
C2:
PF0765312=SH3_2=PU(76.4=80.8)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCTGGACACCACACTCAAG
R:
TAGATCCTCACCACGTCACCC
Band lengths:
179-266
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development