HsaEX6063818 @ hg38
Exon Skipping
Gene
ENSG00000160293 | VAV2
Description
vav guanine nucleotide exchange factor 2 [Source:HGNC Symbol;Acc:HGNC:12658]
Coordinates
chr9:133768442-133772046:-
Coord C1 exon
chr9:133771959-133772046
Coord A exon
chr9:133770378-133770501
Coord C2 exon
chr9:133768442-133768596
Length
124 bp
Sequences
Splice sites
3' ss Seq
TGAGTGTGTACGCCCTGCAGGAG
3' ss Score
6.46
5' ss Seq
CAGGTAACG
5' ss Score
10.52
Exon sequences
Seq C1 exon
GTTCAATGATGAGGTGAAGCACATCAAGGTGGTGGAGAAGGACAACTGGATCCACATCACAGAGGCCAAGAAATTCGACAGCCTCCTG
Seq A exon
GAGTTGGTGGAGTACTACCAGTGCCACTCACTGAAGGAGAGCTTCAAGCAGCTGGACACCACACTCAAGTACCCCTACAAGTCCCGGGAACGTTCGGCCTCCAGGGCCTCCAGCCGGTCCCCAG
Seq C2 exon
TGTTCACGCCCCGCGTCATCGGCACAGCTGTGGCCAGGTATAACTTTGCCGCCCGAGATATGAGGGAGCTTTCGCTGCGGGAGGGTGACGTGGTGAGGATCTACAGCCGCATCGGCGGAGACCAGGGCTGGTGGAAGGGCGAGACCAACGGACGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160293_MULTIEX1-1/2=C1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.030 C2=0.000
Domain overlap (PFAM):
C1:
PF0001719=SH2=FE(38.7=100)
A:
PF0001719=SH2=PD(6.7=11.9)
C2:
PF0765312=SH3_2=PU(76.4=80.8)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCAATGATGAGGTGAAGCACA
R:
GTTGGTCTCGCCCTTCCAC
Band lengths:
235-359
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains