HsaEX0073674 @ hg19
Exon Skipping
Gene
ENSG00000140987 | ZNF434
Description
zinc finger protein 434 [Source:HGNC Symbol;Acc:20812]
Coordinates
chr16:3440010-3443814:-
Coord C1 exon
chr16:3443649-3443814
Coord A exon
chr16:3440423-3440517
Coord C2 exon
chr16:3440010-3440133
Length
95 bp
Sequences
Splice sites
3' ss Seq
GCGGCTGTTTTTTCCCCCAGCCT
3' ss Score
7.47
5' ss Seq
CAGGTGAGC
5' ss Score
9.6
Exon sequences
Seq C1 exon
GTTCTAGATTCTGAGAAGGACTTGAAAGTACTCATGAAGGAGATGGCCCCTTTGGGAGCAACCAGAGAATCACTGAGATCCCAATGGAAACAGGAGGTTCAGCCAGAGGAACCGACTTTTAAGGGATCACAGAGCTCACACCAAAGACCAGGGGAACAGTCAGAAG
Seq A exon
CCTGGCTTGCTCCTCAGGCTCCCAGGAACCTGCCTCAAAACACAGGTCTCCACGACCAGGAGACAGGTGCTGTGGTCTGGACAGCTGGGTCCCAG
Seq C2 exon
GGACCAGCCATGCGTGACAACAGAGCTGTATCCCTCTGTCAGCAAGAATGGATGTGCCCAGGCCCTGCACAAAGGGCCCTCTACAGGGGTGCCACCCAGAGGAAGGACAGTCACGTCTCGCTGG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000140987-'15-20,'15-18,18-20
Average complexity
C2
Mappability confidence:
91%=100=80%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.752 A=1.000 C2=0.128
Domain overlap (PFAM):
C1:
PF0202312=SCAN=PD(3.1=5.4)
A:
PF0202312=SCAN=PD(2.1=6.2)
C2:
PF0135222=KRAB=WD(100=84.6)
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
No conservation detected
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCATGAAGGAGATGGCCCCTT
R:
TGCTGACAGAGGGATACAGCT
Band lengths:
179-274
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)