HsaEX0073675 @ hg19
Exon Skipping
Gene
ENSG00000140987 | ZNF434
Description
zinc finger protein 434 [Source:HGNC Symbol;Acc:20812]
Coordinates
chr16:3434459-3440517:-
Coord C1 exon
chr16:3440423-3440517
Coord A exon
chr16:3440010-3440183
Coord C2 exon
chr16:3434459-3434941
Length
174 bp
Sequences
Splice sites
3' ss Seq
TGTCTCTGCCCCCACCCCAGGCT
3' ss Score
7.31
5' ss Seq
TGGGTAAGG
5' ss Score
9.08
Exon sequences
Seq C1 exon
CCTGGCTTGCTCCTCAGGCTCCCAGGAACCTGCCTCAAAACACAGGTCTCCACGACCAGGAGACAGGTGCTGTGGTCTGGACAGCTGGGTCCCAG
Seq A exon
GCTAGAGTGGTGCTATTTTATCGGTAGCAGCAGCTCCAGTGTTGTTACAGGGACCAGCCATGCGTGACAACAGAGCTGTATCCCTCTGTCAGCAAGAATGGATGTGCCCAGGCCCTGCACAAAGGGCCCTCTACAGGGGTGCCACCCAGAGGAAGGACAGTCACGTCTCGCTGG
Seq C2 exon
CAACAGGTGTGCCCTGGGGCTATGAAGAGACCAAGACGCTCCTGGCTATTCTTAGTAGTTCTCAATTTTATGGAAAACTCCAGACCTGTCAGCAGAACAGCCAGATCTACAGGGCCATGGCGGAAGGACTCTGGGAGCAGGGTTTTCTGCGGACCCCAGAACAGTGTCGCACCAAGTTCAAAAGCCTACAGTTGAGTTACCGCAAAGTGAGGAGAGGCCGTGTGCCTGAGCCTTGTATCTTTTATGAGGAAATGAATGCTCTTTCAGGCTCCTGGGCCTCTGCACCTCCTATGGCAAGCGATGCTGTTCCTGGCCAAGAAGGAAGTGATATTGAGGCTGGAGAGCTGAATCACCAGAATGGGGAACCCACGGAGGTAGAAGATGGCACTGTGGATGGTGCAGACAGGGATGAAAAGGACTTCAGGAATCCTGGCCAGGAAGTCAGGAAACTAGACCTGCCAGTGCTGTTCCCAAACAGACTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000140987-'18-26,'18-19,19-26
Average complexity
C2
Mappability confidence:
92%=100=89%
Protein Impact
Alternative protein isoforms (Ref, Alt. ATG (>10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=0.090 C2=0.345
Domain overlap (PFAM):
C1:
PF0202312=SCAN=PD(2.1=6.2)
A:
PF0135222=KRAB=WD(100=84.6)
C2:
PF138371=Myb_DNA-bind_4=WD(100=53.1)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCTGCCTCAAAACACAGGTC
R:
AGGCTTTTGAACTTGGTGCGA
Band lengths:
255-429
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- The Cancer Genome Atlas (TCGA)
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
- Pre-implantation embryo development
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)