HsaINT0187233 @ hg19
Intron Retention
Gene
ENSG00000140987 | ZNF434
Description
zinc finger protein 434 [Source:HGNC Symbol;Acc:20812]
Coordinates
chr16:3434459-3440183:-
Coord C1 exon
chr16:3440010-3440183
Coord A exon
chr16:3434942-3440009
Coord C2 exon
chr16:3434459-3434941
Length
5068 bp
Sequences
Splice sites
5' ss Seq
TGGGTAAGG
5' ss Score
9.08
3' ss Seq
ACCTATTCTTTGTCCCCCAGCAA
3' ss Score
7.96
Exon sequences
Seq C1 exon
GCTAGAGTGGTGCTATTTTATCGGTAGCAGCAGCTCCAGTGTTGTTACAGGGACCAGCCATGCGTGACAACAGAGCTGTATCCCTCTGTCAGCAAGAATGGATGTGCCCAGGCCCTGCACAAAGGGCCCTCTACAGGGGTGCCACCCAGAGGAAGGACAGTCACGTCTCGCTGG
Seq A exon
GTAAGGATCCATCTTCCCTCCAGGTCAAGGTGGATGTGTTCAGTTGTTCAGAGAGGCTGAAAGGACTTGAGAGGGAGGGAGACAGAGGGAGTGGGGAGACTGTTGGGTGGAGGGAAAGGAGGAAGTAAATGGGGAACCAGAGCAGGCCAGAGAGACACAGGCAGAGATCAAAAGAAAGGGGCAGCATGTGTGACCGGCAGTCAAGAACATGGGAGGTGAAGGGTGAGGCGGTGGAGAAGCAAAATGTTAGTGAGACAGAGTCAGAACAAGTAGTCCAGAGCCGGAGCCAGACAGGTGGCCACCAGGAGCACAGATGTGTTCATGCTGAATGTGCGCTCATGCACACAGGTAGCAGTAGTCGCTCCCGAGTTTCCCCAGTGGCAGAGGAGATTAACAAATAAAACCACCCAACCAGGACAGTCTACTATGCCCAGGCCTTCCGGGAGGAACCAGGCCCTTTCCCAGCATCTCAGGACACTTGGGGAAGGTTCTGCCAAGCAGACCGCTCTCTTGCCTTTCTCAAATCAGTTCTGTCCCATCTGGGCCAAATGCCTCCTCCTCAGAGCAGCCTCCCTGACCATGCAGATTCAGAGACAGACACTGCAGCTCACTGGGCCTAGATTTCTCCTCTGCTGCTTCACATGCAGGGTACTCCTGGCTAAGCCCAGGGTGGGAGGGACTACACAAGGCTGTGAACACAGGCCCTGTGACAGTGCCCCGCCTCACTCTACAATGTTGCCCTCCCCAGTGGTGTGTGGTTTTTCCCTGCTCTGCCCCTGCCATCCCTCCCCTCCTTTGCCAGGAACTCCCAGTTTCCTGGCTTCATCATGTGCCATTTCTTGCTGCTGCTTCAGGCTTCTGCACCTCATCTCTGTCCAGTTGCAGGAGAGTATAGTGTCTTTTTGAGCTCTGTATTGAGATTTGTATTACTAAGTATATATGGATAATACAATAAGGTGAGATATAAATATTTTTGTACTTGTGATTTTTAACTTATTAGGTGAAATTCACATGACATAAAATTAACCACTGTAAAGTGAACAATTCTTTGGCCTCTAGCACTTTCAGAGTGTTGTATAATTACCACCACGTCCAGTTCCAGAACCTTTCCATCTCTCCAAAGTAAGGTCCCACAACCATCCAGCAGTTTCTCCCCGTCCTTCCCCTGCAAGCCCTTTGCAGACACCAGTCTTCATTCTGTCTCTGTGGATTGAGCTATTCTGAATATTTCATGTAATGGTACCTGTAATTTTAACTGCTACAACATTAGGCTTATTGAATGAGGGCTTGTATTCCCCACACACTTTTGGTTTCTTGTCAACCATTGAGGATCCTTTAAAATTAGAGGTAAGAGTTGAGACAGAATGTGAGAGGACAAGTCATTCTTTCCACAAATATTAATTTAGTGCCTACAGTATCTCAGACCTAGTTCTAGGTCGTTAGGGATACAACAGTGAACAAACAGATAAAGATTCCTGCCCTGTGGGAAGAGACAGACCATAGCATAATCAGTAAGCGGCAGAAGATGTTAGAGGGCGATAAGCGCAATGGGAGAGAAGCAGCAGCAGAGCAGCGTGATGGGAGTGCTAGGGCAGAGGTTGGTTTGCAGTTTTCAGTTTGGGTCCTCAGGGTCGCCCTCACTGAGAAAATGACATTTGAAAAGACTTGCTGAAGGAGGAGGGATGAGCTATGCAGCCATATCCTACATGGAGGAAGAGTGTAAGACAGACGCAATGACTTGGGCTGGAGCGAGGTGGGCATGCCAGTTCACTGGCACAGAGTACACCCATGAGTAATGAGAAAACGAGCTCAGAAAGCCAGATCAAATGAGTGCTGCTAGCTGAGACTGAGAGGGAGCAATTAGAAACTTTTATAACAATTTGACACTGCTGCACTATTCGGTTGCATTTTTATTGTATTTTACAAAAGAAATAAGCACAAGACTCCTGTCCTTCATAGATAATTTGAGAAGTACTAATATGGGATCATGAGGCCCTACATGAAGGACTTTTTTCTTCTGAGTGAAATGGGGGAGCCTTGTGCGGTTCTGGGCAGAGGAGTAATAGTTTTAAAAGGACCACTTTGAGTATGTCACTTTATTTGGCACTTAACTCTACGTAAACATTTATTTGTGTCTCTTTTTGCTGGAGAGACTTCTATAGGACTGTGACCTCCTTGAAGGCAGGGTTCATGTAATATTTATATTTCTCAGAAACTGGCATTGTAGGCACTCAGTGTTAGTTAAATTGAATAACAAAGGAGGGGACTCCCTCTGGCTGTTGGGTTGAAAGTAGACCGTAGAAGGTCCAGAGTGGAAGCAAGAAGACCAGATAGGCTATGGCAGTGATCCAGGCATGAGGTGATGGTGGCTCAGTGTGGAGAAGAGGGGGTGACAAGAAGAGGCTGGTGCGCTTCAGAGCATCATGACCAGATGTTGGAATGCACTTGCTGGGACAGCTCTAGTCAAATCGGTCCTCATGAACTGGCCCAGATGGGCAGCAGGTGTGTGTGGTGAGGGTTATTTAGTAGCCAGCCATCCTGAACTGCTCTTCTCAGATGTTTACTACTTATTCTTACCTTGGTGTGTTAACTGCTGTCATTTAGTTTCCTGTATCTACAAGGATGACAGGAGATATAAACAGATAGAGATGGGCTGGCTGAGGAGGTATTCCTGTATCAGGGAGGGAACAGGCAGATATATCGTTACAACCAGCTCCTCTGTCCCCTGAATCTTTGCTTTCCTTGAGTATCACCTGTTCACTGTGTCCTCTTATGTGGCCACCCTCAGGAAGTCCCACAACTGTCAAGGCAGGCAAGCCACTACCCTTATTGCCAGCCACCTCTCCAGGAGGAATGAGTAGGATTGAGGATAATTAACGAGAAATTAAATAGGCAGCTTTAGTAAATAACCCTATAAGTCATTATCAGTGGAGGGAATGTCTTTTGTATTATACTAAAAGTTTTCATGTTTTAGACAAAAAGCCACAGTGAGATTTCTTCCTAGAAATAACAATAGCCAGTTGTGGCACGGTTTGAGAAACCAGGATGTAACTTTTTTTTTTTTTTTTTTTATACTTTAAGCTTTAAGGTACATGTGCACAAAGTGCAGGTTAGTTACATATGTATACATGTGCCATGTTGGTGTGCTGCACCCATGAACTCGTCATTTAACATTAGGTATATCTCCAAATGCTATCCCTCCCCTCTCTCCCCACCCCACAACAGGCCTCCGTGTGTGATGTTCCCCTACCTGTGTCCATGTGTTCTCACTGTTCAGTTACAACCTATGAGTGACAACATGTGGTATTTGGTTTTTTGTCCTCGCAATAGTTTGCTGAGAATGATGGTTTCCAGCTTCATCCATGTCCCTACAAAGGACATGAACTCATCATTTTTTATGGTTGCATAGTATTCCATGGTGTATACATGCCACATTTTCTTAATCCAGTCTATCATTGTTGGACATTTGGCTTGGTTCCAAGTCTTTGCTGTTGTGAATAGTGCCGCAATAAACATACGTGTGCATGTGTCTTTATAGCAGCATGATTTATAATCCTTTGGGTATACACCTAGTAATGGGATTGCTGGGTCAAATGGTATTTCTGGTTCTAGATCCCTGAGGAATCGCGACACTGACTTCCACAATGGTTGAACTAGTTTACAGTCCCACCAACAGTGTAAAAGTGTTCCTATTTCTCCACATCCTCTCCAGCACCTGTTGTTTCCTGACTTTTTAATGATTGCCATTCTAACTGGTGTGAGATGGTATCTCATTGTAGTTTTGATTTGCATTTCTCTGATGGCCAGTGATGATGAGCATTTTTTCATGTGTCTTTTGGCTGCATAAATGTCTTCTTTTGAGAAGTGTCTGTTCATATCCTTTGCCCACTTTTTGATGGGGTTGTTTTTTTCTTGTAAATTTGTTAGAGTTCATTGTAGATTCTGGATATTAGCCCTTTGTCAGATGAGTAGATTGCAAAAATTTTCTCCCATTCTGTAGGTTGCCTGTTCACTCTGATGGTAGTTTCTTTTGCTGTGCAGAAGCTCTTTGGTTTAATTAGATCCCATTTGTCAATTTTGGCTTTGGTTGCCATTGCTTTTGGTGTTTTAGACATGAAGTCCTTGCCCATGCCTATGTCCTGAATGGTAATGCCTAGGTTTTCTTCTAGGGTTTTTATGGTTTTAGGTCTAACGTTTAAGTCTTTAATCCTTCTTGAATTAATTTTTGTATAAGGTGTAAGGAAGGGATCCAGTTTCAGCTTTCTACATATGGCTAGCCAGGTTTCCCAGCACCATTTATTAAATAGGGAATCCTTTCCCCATTGCTTGTTTTTGTCAGGTTTGTCAAAGATCAGATGGTTGTAGATATGCGGCATTATTTCTGAGGGCTCTGTGCTGTTCCATTGGTCTATTTCTCTGTTTTTGTACCAGTACCATGCTGTTTTGGTTACTGTAGCCTTGTAGTATAGTTTGAAGTCAGGTAGCGTGATGCCTCCAGCTTTGTTCTTTTGGCTTAGGATTGACTTGGCAATGCGGGCTCTTTTTTGGTTCCATATAAACTTTAAAGTAGTTTTTTCCAATTCTGTGAAGAAAGTCATTGGTAGCTTGATGGGGATGGCATTGAATCTATAAATTACCTTGAGCAGTATGGCCATTTTCACGATATTGATTTTTCCTACCCATGAGCATGGCATTCTCTCTCTGTCATCAGGCTGGAGTGCAGTGGCACAATCTCAGCTCACTGCAACCTCTGCCTCCTGGGTTCAAGTGATTCTTCTTCCTCAGCCTCCTGAGTAGCTGGGACTACAGGCACACGGCACCACACCCAGCTATTTTTTGTTGTATTTTTAGTAGAGACGGGGTTTCACCATGTTGGCCAGGATGGTCTCGATCTCTTGACCTCATGATCTGCCCGCCTTGGCCTCCCAAAGTGCTGGGATTACAGGTGTGAGCCACCGCATCCAGCCTAGGATGTAACTTTTTAAGCTGCCAAAACTGCACACTGCAGTATGTACAGTCCTCCATGATCTAACTGACAGATCTAATTGACCTATTCTTTGTCCCCCAG
Seq C2 exon
CAACAGGTGTGCCCTGGGGCTATGAAGAGACCAAGACGCTCCTGGCTATTCTTAGTAGTTCTCAATTTTATGGAAAACTCCAGACCTGTCAGCAGAACAGCCAGATCTACAGGGCCATGGCGGAAGGACTCTGGGAGCAGGGTTTTCTGCGGACCCCAGAACAGTGTCGCACCAAGTTCAAAAGCCTACAGTTGAGTTACCGCAAAGTGAGGAGAGGCCGTGTGCCTGAGCCTTGTATCTTTTATGAGGAAATGAATGCTCTTTCAGGCTCCTGGGCCTCTGCACCTCCTATGGCAAGCGATGCTGTTCCTGGCCAAGAAGGAAGTGATATTGAGGCTGGAGAGCTGAATCACCAGAATGGGGAACCCACGGAGGTAGAAGATGGCACTGTGGATGGTGCAGACAGGGATGAAAAGGACTTCAGGAATCCTGGCCAGGAAGTCAGGAAACTAGACCTGCCAGTGCTGTTCCCAAACAGACTTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000140987-ZNF434:NM_017810:4
Average complexity
IR-S
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence inclusion (1st CDS intron)
No structure available
Features
Disorder rate (Iupred):
C1=0.090 A=NA C2=0.345
Domain overlap (PFAM):
C1:
PF0135222=KRAB=WD(100=84.6)
A:
NA
C2:
PF138371=Myb_DNA-bind_4=WD(100=53.1)
Main Inclusion Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
Associated events
Other assemblies
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
No suggested primer sequences
R:
No suggested primer sequences
Band lengths:
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Genotype-Tissue Expression Project (GTEx)
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)