HsaEX1011914 @ hg38
Exon Skipping
Gene
ENSG00000158486 | DNAH3
Description
dynein axonemal heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:2949]
Coordinates
chr16:21134259-21140710:-
Coord C1 exon
chr16:21140536-21140710
Coord A exon
chr16:21136324-21136513
Coord C2 exon
chr16:21134259-21134454
Length
190 bp
Sequences
Splice sites
3' ss Seq
TGGTGGTTTGTTTATGGAAGAGA
3' ss Score
0.14
5' ss Seq
TCGGTAAGG
5' ss Score
10.48
Exon sequences
Seq C1 exon
GATCAAGTTGGCCTTCAAGACGTCAATCTTCTCACCCATGAAGAAGGAGGTAAAGACATCTTTGACGTTCCCAGGAAGCAGACCAATGAGTCCAGAACAGCAGCTCGATGTCATGTTACAGCAGGAGATGGAAATGGAAAGTAAAGAAAAGAAGCCATCTGAATCGGACCTGGAG
Seq A exon
AGATACTATTACTATCTGACCAATGGAATTCGCAAAGACATGATTGCCCCTGAGGAGGGTGAAGTGATGGTTCGGATTTCAAAGCTGATTTCTAACACGCTGCTGACGAGTCCCTTCCTGGAGCCCCTGATGGTGGTCCTCGTGCAGGAGAAGGAGAATGACTATTACTGTAGCCTCATGAAAAGCATCG
Seq C2 exon
TTGATTACATCCTCATGGACCCAATGGAGAGAAAACGGCTCTTTATTGAGAGCATCCCCCGCTTGTTTCCTCAAAGAGTGATCCGGGCCCCTGTGCCCTGGCACAGTGTCTACAGGAGCGCCAAGAAGTGGAACGAGGAGCATCTGCACACGGTGAACCCCATGATGCTCAGGCTGAAAGAACTGTGGTTTGCAGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486-'10-14,'10-13,13-14
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.525 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCCAGGAAGCAGACCAATGA
R:
CTCCTCGTTCCACTTCTTGGC
Band lengths:
247-437
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains