HsaEX1012536 @ hg38
Exon Skipping
Gene
ENSG00000077380 | DYNC1I2
Description
dynein cytoplasmic 1 intermediate chain 2 [Source:HGNC Symbol;Acc:HGNC:2964]
Coordinates
chr2:171712767-171726852:+
Coord C1 exon
chr2:171712767-171712826
Coord A exon
chr2:171715328-171715350
Coord C2 exon
chr2:171715390-171726852
Length
23 bp
Sequences
Splice sites
3' ss Seq
TTTGTATTTACTTAATTTAGACG
3' ss Score
4.24
5' ss Seq
GAATGGCTA
5' ss Score
-25.19
Exon sequences
Seq C1 exon
GACGCTGCATTGGGATACAGATCCATCAGTTCTTCAGCTTCACTCAGATTCCGATTTGGG
Seq A exon
ACGAGGACCTATTAAACTTGGAA
Seq C2 exon
TTGTCACGTATACAAAGGAAACTCAGACTCCAGTTATGGCTCAACCCAAAGAAGGTGAATATCTATCCTTAGTATAATTGTCATTGAGCACCTATGTTAAATACATAGATTCTTTTTTTCTTCCTTTGATTTTTGTTTTGTTTCTTTTTTGCTTTTGTGTTTTGGCATGTTTTCTTAGGGAAACATGAGAAAACTAATGCTTTACAGTTTCTGTATTTATGTCTTCATTTTTTCGAGTTTTAAAACTTATTAGAAGTTAACGTTGTAAGCTGTATGTGTGGTTTCTTAATTTTGTTGACATAAATTTAAGTCTTTCAGCCCTTATTTTGTCATTAATGTATACTGCTTTTAGAAGCCAAAAAGCTTAAGAATTTTCTGTTTCTGTCATTGAGCATAATTCTTCCCCAAAAGAGAGTGGGTCCCATAGTAAACAAAGTCATGTAAATTATTTCTGAAAAGCATACTGTACCCTGATGTTATTCATACTAATGAACAAATCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000077380-'26-34,'26-33,27-34
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=0.883 C2=NA
Domain overlap (PFAM):
C1:
PF115403=Dynein_IC2=PU(0.1=0.0)
A:
NO
C2:
NA
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACGCTGCATTGGGATACAGA
R:
CACCTTCTTTGGGTTGAGCCA
Band lengths:
117-140
Functional annotations
There are 1 annotated functions for this event
PMID: 17551010
This event
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001218; ELM sequence: YTKETQT; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains