MmuEX6102088 @ mm10
Exon Skipping
Gene
ENSMUSG00000027012 | Dync1i2
Description
dynein cytoplasmic 1 intermediate chain 2 [Source:MGI Symbol;Acc:MGI:107750]
Coordinates
chr2:71228600-71246784:+
Coord C1 exon
chr2:71228600-71228690
Coord A exon
chr2:71235915-71236030
Coord C2 exon
chr2:71246689-71246784
Length
116 bp
Sequences
Splice sites
3' ss Seq
ATTTATATTCACTTATTTAGACG
3' ss Score
5.34
5' ss Seq
AAGGTGAGT
5' ss Score
10.47
Exon sequences
Seq C1 exon
TCCCTCCTCCTATGTCTCCATCCTCCAAGTCGGTGAGCACGCCAAGTGAAGCTGGAAGCCAGGATTCTGGAGATGGCGCCGTGGGATCTAG
Seq A exon
ACGAGGACCTATTAAACTTGGAATGGCCAAAATTACTCAAGTTGACTTTCCCCCTCGAGAAATCGTCACATACACAAAGGAAACTCAGACCCCGGTTACAGCTCAACCCAAAGAAG
Seq C2 exon
ATGAGGAGGAGGAAGATGATGTAGCAACTCCTAAACCTCCTGTTGAACCTGAAGAAGAGAAAACTTTGAAAAAAGACGAAGAGAATGATAGCAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000027012-'16-32,'16-24,22-32
Average complexity
C1
Mappability confidence:
95%=89=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=0.940 C2=1.000
Domain overlap (PFAM):
C1:
PF115403=Dynein_IC2=PU(0.1=0.0)
A:
PF115403=Dynein_IC2=WD(100=82.5)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCCTCCTCCTATGTCTCCATCC
R:
CTTTGCTATCATTCTCTTCGTCTT
Band lengths:
186-302
Functional annotations
There are 1 annotated functions for this event
PMID: 17551010
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001218; ELM sequence: YTKETQT; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types