DreEX0028602 @ danRer10
Exon Skipping
Gene
ENSDARG00000103195 | dync1i2b
Description
dynein, cytoplasmic 1, intermediate chain 2b [Source:ZFIN;Acc:ZDB-GENE-090121-1]
Coordinates
chr6:3781214-3783193:+
Coord C1 exon
chr6:3781214-3781273
Coord A exon
chr6:3782022-3782137
Coord C2 exon
chr6:3783107-3783193
Length
116 bp
Sequences
Splice sites
3' ss Seq
AGTTTGCTGTATTTCTGCAGACG
3' ss Score
6.99
5' ss Seq
AGGGTAAAA
5' ss Score
4.51
Exon sequences
Seq C1 exon
GACTCTTCACTGGGACTCTGATCCTTCTACTCTACTGCTCCATTCAGACTCTCAGCTCGG
Seq A exon
ACGTGGCCCGCTTAAGTTGGGCATGTCGAAGGTCACACAGGTGGACTTTCCTCCTAAAGAGATGGTGTCGTACTCAAAAGAGACCCAGACACCCACACAGACTCATCACAAAGAGG
Seq C2 exon
ATGAAGAGGAGGAGGAAGATTTGGCTGTGATGCAGCCTGTAATGGAGCCTCAAGAGGAGAAAGACTCTCAGAAAGAAGAAGATGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000103195-'4-9,'4-8,5-9
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=1.000 A=1.000 C2=1.000
Domain overlap (PFAM):
C1:
PF115403=Dynein_IC2=PU(0.1=0.0)
A:
PF115403=Dynein_IC2=WD(100=82.5)
C2:
NO
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTCTTCACTGGGACTCTGATCC
R:
CTTCATCTTCTTCTTTCTGAGAGTCT
Band lengths:
146-262
Functional annotations
There are 1 annotated functions for this event
PMID: 17551010
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: . ELM ID: ELMI001218; ELM sequence: YTKETQT; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]