HsaEX6000987 @ hg19
Exon Skipping
Gene
ENSG00000011405 | PIK3C2A
Description
phosphoinositide-3-kinase, class 2, alpha polypeptide [Source:HGNC Symbol;Acc:8971]
Coordinates
chr11:17158029-17167489:-
Coord C1 exon
chr11:17167410-17167489
Coord A exon
chr11:17167215-17167278
Coord C2 exon
chr11:17158029-17158172
Length
64 bp
Sequences
Splice sites
3' ss Seq
ATAACTGTTGTTTCTTTCAGACA
3' ss Score
9.66
5' ss Seq
GAAGTAAGT
5' ss Score
9.82
Exon sequences
Seq C1 exon
GCAGAAGATGATGAAACACCCGTGGATTTAAACAAACACCTGTATCAAATAGAAAAACCTTGCAAAGAAGCCATGACGAG
Seq A exon
ACACCCTGTTGAAGAACTCTTAGATTCTTATCACAACCAAGTAGAACTGGCTCTTCAAATTGAA
Seq C2 exon
AACCAACACCGAGCAGTAGATCAAGTAATTAAAGCTGTAAGAAAAATCTGTAGTGCTTTAGATGGTGTCGAGACTCTTGCCATTACAGAATCAGTAAAGAAGCTAAAGAGAGCAGTTAATCTTCCAAGGAGTAAAACTGCTGAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011405-'5-8,'5-6,6-8=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.037 A=0.045 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
NO
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCCGTGGATTTAAACAAACACC
R:
GGCAAGAGTCTCGACACCATC
Band lengths:
145-209
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)