HsaEX6000994 @ hg19
Exon Skipping
Gene
ENSG00000011405 | PIK3C2A
Description
phosphoinositide-3-kinase, class 2, alpha polypeptide [Source:HGNC Symbol;Acc:8971]
Coordinates
chr11:17126716-17134213:-
Coord C1 exon
chr11:17134121-17134213
Coord A exon
chr11:17131979-17132108
Coord C2 exon
chr11:17126716-17126852
Length
130 bp
Sequences
Splice sites
3' ss Seq
TTTGTTTCCTTGATTTCAAGGTT
3' ss Score
7.95
5' ss Seq
GAGGTAAGT
5' ss Score
11.08
Exon sequences
Seq C1 exon
TCGTGTTCCTTCTTCAGTTCTAATGCTGTCCCCCTAAAAGTCACAATGGTGAATGCTGACCCTATGGGAGAAGAAATTAATGTCATGTTTAAG
Seq A exon
GTTGGTGAAGATCTTCGGCAAGATATGTTAGCTTTACAGATGATAAAGATTATGGATAAGATCTGGCTTAAAGAAGGACTAGATCTGAGGATGGTAATTTTCAAATGTCTCTCAACTGGCAGAGATCGAG
Seq C2 exon
GCATGGTGGAGCTGGTTCCTGCTTCCGATACCCTCAGGAAAATCCAAGTGGAATATGGTGTGACAGGATCCTTTAAAGATAAACCACTTGCAGAGTGGCTAAGGAAATACAATCCCTCTGAAGAAGAATATGAAAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000011405-'21-23,'21-22,22-23=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0045422=PI3_PI4_kinase=PU(2.8=19.4)
A:
PF0045422=PI3_PI4_kinase=FE(19.9=100)
C2:
PF0045422=PI3_PI4_kinase=FE(20.8=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTGTTCCTTCTTCAGTTCTAATGC
R:
TTCATATTCTTCTTCAGAGGGATTGT
Band lengths:
226-356
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)