HsaEX6002226 @ hg38
Exon Skipping
Gene
ENSG00000013725 | CD6
Description
CD6 molecule [Source:HGNC Symbol;Acc:HGNC:1691]
Coordinates
chr11:60971680-61013563:+
Coord C1 exon
chr11:60971680-60971914
Coord A exon
chr11:61007560-61007618
Coord C2 exon
chr11:61013423-61013563
Length
59 bp
Sequences
Splice sites
3' ss Seq
CTCTGGTCTGACACTTCCAGGGG
3' ss Score
6.87
5' ss Seq
GAGGTGCGG
5' ss Score
6.79
Exon sequences
Seq C1 exon
ACTCACAGGTTGGGTTTGATCGCATGCGTGTCGGAGAGGAGAGAGCAGAGAGAGACACAGGAACAAGAACAGCAAAGGGTAGAGCAGACCTGCGCCAGGGGCGCACAACGGCCGTGTCCACCTCCCGGCCCCAAGATGGTGCTTCCCACAGGCAGCCACGCGTAGCAGCCAGAGACAGCTCCAGACATGTGGCTCTTCTTCGGGATCACTGGATTGCTGACGGCAGCCCTCTCAG
Seq A exon
GGGAGCGGCTTCCGGTCCGTCTGACAAACGGGAGCAGCAGCTGCAGCGGGACGGTGGAG
Seq C2 exon
AATCTTCTGTGACAGTGAAAATAGAGAACAAGGAATCTCGGGAGCTAATGCTCCTCATCCCCTCCATCGTTCTGGGAATTCTCCTCCTTGGCTCCCTCATCTTCATAGCCTTCATCCTCTTGAGAATTAAAGGAAAATATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000013725_MULTIEX2-4/13=C1-10
Average complexity
C3
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.125 A=0.237 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0053013=SRCR=WD(100=92.4)
C2:
PF151021=TMEM154=PD(52.9=95.8)
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGGATCACTGGATTGCTGACG
R:
GAGGGAGCCAAGGAGGAGAAT
Band lengths:
132-191
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains