HsaEX6003890 @ hg19
Exon Skipping
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:7606]
Coordinates
chr11:76918334-76919848:+
Coord C1 exon
chr11:76918334-76918447
Coord A exon
chr11:76919475-76919562
Coord C2 exon
chr11:76919742-76919848
Length
88 bp
Sequences
Splice sites
3' ss Seq
TTCGATGGCCCTGACCCCAGGTC
3' ss Score
5.45
5' ss Seq
ACGGTAATG
5' ss Score
6.53
Exon sequences
Seq C1 exon
GCCTTCGAAGTGGAGTCCAGCACCAAGGCCAAGGACTTCTGCCAGAACATCGCCACCAGGCTGCTCCTCAAGTCCTCAGAGGGATTCAGCCTCTTTGTCAAAATTGCAGACAAG
Seq A exon
GTCCTCAGCGTTCCTGAGAATGACTTCTTCTTTGACTTTGTTCGACACTTGACAGACTGGATAAAGAAAGCTCGGCCCATCAAGGACG
Seq C2 exon
GAATTGTGCCCTCACTCACCTACCAGGTGTTCTTCATGAAGAAGCTGTGGACCACCACGGTGCCAGGGAAGGATCCCATGGCCGATTCCATCTTCCACTATTACCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474-'53-62,'53-61,54-62=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF093795=FERM_N=FE(39.4=100)
A:
PF093795=FERM_N=FE(30.9=100)
C2:
PF093795=FERM_N=PD(18.1=47.2),PF0037313=FERM_M=PU(10.8=33.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCAAGGCCAAGGACTTCTG
R:
GAATCGGCCATGGGATCCTTC
Band lengths:
182-270
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)