HsaEX6003917 @ hg19
Exon Skipping
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:7606]
Coordinates
chr11:76858844-76867827:+
Coord C1 exon
chr11:76858844-76858996
Coord A exon
chr11:76866953-76867137
Coord C2 exon
chr11:76867706-76867827
Length
185 bp
Sequences
Splice sites
3' ss Seq
CCATCTCTTGCTGCCCGCAGACG
3' ss Score
10.48
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
Exon sequences
Seq C1 exon
GAACACTGGATCTCTCCGCAGAACGCAACGCACATCAAGCCTATGCACCCCACGTCGGTCCACGGCGTGGAGGACATGATCCGCCTGGGGGACCTCAACGAGGCGGGCATCTTGCGCAACCTGCTTATCCGCTACCGGGACCACCTCATCTAC
Seq A exon
ACGTATACGGGCTCCATCCTGGTGGCTGTGAACCCCTACCAGCTGCTCTCCATCTACTCGCCAGAGCACATCCGCCAGTATACCAACAAGAAGATTGGGGAGATGCCCCCCCACATCTTTGCCATTGCTGACAACTGCTACTTCAACATGAAACGCAACAGCCGAGACCAGTGCTGCATCATCAG
Seq C2 exon
TGGGGAATCTGGGGCCGGGAAGACGGAGAGCACAAAGCTGATCCTGCAGTTCCTGGCAGCCATCAGTGGGCAGCACTCGTGGATTGAGCAGCAGGTCTTGGAGGCCACCCCCATTCTGGAAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474-'4-6,'4-5,6-6=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.118 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PU(4.2=54.9)
A:
PF0006316=Myosin_head=FE(9.2=100)
C2:
PF0006316=Myosin_head=FE(6.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACACTGGATCTCTCCGCAGAA
R:
CCAAGACCTGCTGCTCAATCC
Band lengths:
252-437
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)