HsaEX6003917 @ hg38
Exon Skipping
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:HGNC:7606]
Coordinates
chr11:77147798-77161115:+
Coord C1 exon
chr11:77147798-77147950
Coord A exon
chr11:77155907-77156091
Coord C2 exon
chr11:77160973-77161115
Length
185 bp
Sequences
Splice sites
3' ss Seq
CCATCTCTTGCTGCCCGCAGACG
3' ss Score
10.48
5' ss Seq
CAGGTGGGC
5' ss Score
8.07
Exon sequences
Seq C1 exon
GAACACTGGATCTCTCCGCAGAACGCAACGCACATCAAGCCTATGCACCCCACGTCGGTCCACGGCGTGGAGGACATGATCCGCCTGGGGGACCTCAACGAGGCGGGCATCTTGCGCAACCTGCTTATCCGCTACCGGGACCACCTCATCTAC
Seq A exon
ACGTATACGGGCTCCATCCTGGTGGCTGTGAACCCCTACCAGCTGCTCTCCATCTACTCGCCAGAGCACATCCGCCAGTATACCAACAAGAAGATTGGGGAGATGCCCCCCCACATCTTTGCCATTGCTGACAACTGCTACTTCAACATGAAACGCAACAGCCGAGACCAGTGCTGCATCATCAG
Seq C2 exon
GGGATCTACGGGCGGCTGTTCGTGTGGATTGTGGACAAGATCAACGCAGCAATTTACAAGCCTCCCTCCCAGGATGTGAAGAACTCTCGCAGGTCCATCGGCCTCCTGGACATCTTTGGGTTTGAGAACTTTGCTGTGAACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474_MULTIEX4-1/7=C1-C2
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.155 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006316=Myosin_head=PU(4.2=54.9)
A:
PF0006316=Myosin_head=FE(9.2=100)
C2:
PF0006316=Myosin_head=FE(7.1=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACACTGGATCTCTCCGCAGAA
R:
TGGACCTGCGAGAGTTCTTCA
Band lengths:
248-433
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains