HsaEX6003918 @ hg19
Exon Skipping
Gene
ENSG00000137474 | MYO7A
Description
myosin VIIA [Source:HGNC Symbol;Acc:7606]
Coordinates
chr11:76853755-76867137:+
Coord C1 exon
chr11:76853755-76853868
Coord A exon
chr11:76858844-76858996
Coord C2 exon
chr11:76866953-76867137
Length
153 bp
Sequences
Splice sites
3' ss Seq
GACGTTCTGGCTCCCCGCAGGAA
3' ss Score
11.45
5' ss Seq
TACGTGAGT
5' ss Score
7.77
Exon sequences
Seq C1 exon
GGGGACCATGTGTGGATGGACCTGAGATTGGGGCAGGAGTTCGACGTGCCCATCGGGGCGGTGGTGAAGCTCTGCGACTCTGGGCAGGTCCAGGTGGTGGATGATGAAGACAAT
Seq A exon
GAACACTGGATCTCTCCGCAGAACGCAACGCACATCAAGCCTATGCACCCCACGTCGGTCCACGGCGTGGAGGACATGATCCGCCTGGGGGACCTCAACGAGGCGGGCATCTTGCGCAACCTGCTTATCCGCTACCGGGACCACCTCATCTAC
Seq C2 exon
ACGTATACGGGCTCCATCCTGGTGGCTGTGAACCCCTACCAGCTGCTCTCCATCTACTCGCCAGAGCACATCCGCCAGTATACCAACAAGAAGATTGGGGAGATGCCCCCCCACATCTTTGCCATTGCTGACAACTGCTACTTCAACATGAAACGCAACAGCCGAGACCAGTGCTGCATCATCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000137474-'3-5,'3-3,4-5=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.026 A=0.118 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0006316=Myosin_head=PU(4.2=54.9)
C2:
PF0006316=Myosin_head=FE(9.2=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGATGGACCTGAGATTGGGG
R:
TAGCAGTTGTCAGCAATGGCA
Band lengths:
242-395
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)