HsaEX6005533 @ hg38
Exon Skipping
Gene
ENSG00000120457 | KCNJ5
Description
potassium voltage-gated channel subfamily J member 5 [Source:HGNC Symbol;Acc:HGNC:6266]
Coordinates
chr11:128891356-128921035:+
Coord C1 exon
chr11:128891356-128891721
Coord A exon
chr11:128911264-128912210
Coord C2 exon
chr11:128916409-128921035
Length
947 bp
Sequences
Splice sites
3' ss Seq
GGTGTCTTTTTAACTCAAAGCAT
3' ss Score
4.18
5' ss Seq
CAGGTAAGG
5' ss Score
11.08
Exon sequences
Seq C1 exon
ATTTGTACCAGGGACGGAGGGAGAGAGGAGAGGGAGGAGGGGACACACACACACACACACACACACACACACACACACACACACACAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGAGATTGTTCCAGCTGCTCTCGCTAGAGAAAGGGAGTGACCCAAGGGGCCGCGAGTGAAGGGACAGGATGGCTTAGGTACCTCTGCCCACAGGACCCCACAACAGGGAGAGGTTCCAGCTACAGCTCCTCCGTGGGGTCATGGCAGGGGCTGGGGAGTCCCCTCAAAAGCCCTGAGCCCCCCTGCACCGCCGCTAAGGGACACCCCAGAAGTTAGCATCAGTGGGACTCGGAAGCTCCGATCTCAACAA
Seq A exon
CATCCCAGCTATGGCTGGCGATTCTAGGAATGCCATGAACCAGGACATGGAGATTGGAGTCACTCCCTGGGACCCCAAGAAGATTCCAAAACAGGCCCGCGATTATGTCCCCATTGCCACAGACCGTACGCGCCTGCTGGCCGAGGGCAAGAAGCCACGCCAGCGCTACATGGAGAAGAGTGGCAAGTGCAACGTGCACCACGGCAACGTCCAGGAGACCTACCGGTACCTGAGTGACCTCTTCACCACCCTGGTGGACCTCAAGTGGCGCTTCAACTTGCTCGTCTTCACCATGGTTTACACTGTCACCTGGCTGTTCTTCGGCTTCATTTGGTGGCTCATTGCTTATATCCGGGGTGACCTGGACCATGTTGGCGACCAAGAGTGGATTCCTTGTGTTGAAAACCTCAGTGGCTTCGTGTCCGCTTTCCTGTTCTCCATTGAGACCGAAACAACCATTGGGTATGGCTTCCGAGTCATCACAGAGAAGTGTCCAGAGGGGATTATACTCCTCTTGGTCCAGGCCATCCTGGGCTCCATCGTCAATGCCTTCATGGTGGGGTGCATGTTTGTCAAGATCAGCCAGCCCAAGAAGAGAGCGGAGACCCTCATGTTTTCCAACAACGCAGTCATCTCCATGCGGGACGAGAAGCTGTGCCTCATGTTCCGGGTGGGCGACCTCCGCAACTCCCACATCGTGGAGGCCTCCATCCGGGCCAAGCTCATCAAGTCCCGGCAGACCAAAGAGGGGGAGTTCATCCCCCTGAACCAGACAGACATCAACGTGGGCTTTGACACGGGCGACGACCGCCTCTTCCTTGTGTCTCCTCTGATCATCTCCCATGAGATCAACCAGAAGAGCCCTTTCTGGGAGATGTCTCAGGCTCAGCTGCATCAGGAAGAGTTTGAAGTTGTGGTCATTCTAGAAGGGATGGTGGAAGCCACAG
Seq C2 exon
GCATGACCTGCCAAGCCCGGAGCTCCTACATGGATACAGAGGTGCTCTGGGGCCACCGATTCACACCAGTCCTCACCTTGGAAAAGGGCTTCTATGAGGTGGACTACAACACCTTCCATGATACCTATGAGACCAACACACCCAGCTGCTGTGCCAAGGAGCTGGCAGAAATGAAGAGGGAAGGCCGGCTCCTCCAGTACCTCCCCAGCCCCCCACTGCTGGGGGGCTGTGCTGAGGCAGGGCTGGATGCAGAGGCTGAGCAGAATGAAGAAGATGAGCCCAAGGGGCTGGGTGGGTCCAGGGAGGCCAGGGGCTCGGTGTGAGGGGTGCAGCCTCCCTAAGACCTCCTGTCACTGGCTTCAGTGAACACAGACACTGCAGAGCCTGGGAGCAGGGGAGGGGAATAGTTGAGTGTGCTGTTTGGGGGCTCAGGAGCCATCAAGGCTGTGGGGAGGAACCATAAACCCAGCCCTCACAGCTCCCAGCACAGGGCCTCCCTG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000120457_MULTIEX1-2/2=C1-C2
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion (Ref, Alt. ATG (<=10 exons))
No structure available
Features
Disorder rate (Iupred):
C1=NA A=0.010 C2=0.280
Domain overlap (PFAM):
C1:
NA
A:
PF0100715=IRK=PU(77.5=82.7)
C2:
PF0100715=IRK=PD(22.2=68.5)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTAGGTACCTCTGCCCACAGG
R:
TCATTTCTGCCAGCTCCTTGG
Band lengths:
351-1298
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains