HsaEX6006568 @ hg38
Exon Skipping
Gene
ENSG00000160255 | ITGB2
Description
integrin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6155]
Coordinates
chr21:44885953-44888895:-
Coord C1 exon
chr21:44888693-44888895
Coord A exon
chr21:44886736-44886902
Coord C2 exon
chr21:44885953-44886430
Length
167 bp
Sequences
Splice sites
3' ss Seq
GTGTGCTGCTTCTTCCCTAGAGT
3' ss Score
9.54
5' ss Seq
AATGTAAGT
5' ss Score
8.62
Exon sequences
Seq C1 exon
CTCCTGCGCCGAGTGCCTGAAGTTCGAAAAGGGCCCCTTTGGGAAGAACTGCAGCGCGGCGTGTCCGGGCCTGCAGCTGTCGAACAACCCCGTGAAGGGCAGGACCTGCAAGGAGAGGGACTCAGAGGGCTGCTGGGTGGCCTACACGCTGGAGCAGCAGGACGGGATGGACCGCTACCTCATCTATGTGGATGAGAGCCGAG
Seq A exon
AGTGTGTGGCAGGCCCCAACATCGCCGCCATCGTCGGGGGCACCGTGGCAGGCATCGTGCTGATCGGCATTCTCCTGCTGGTCATCTGGAAGGCTCTGATCCACCTGAGCGACCTCCGGGAGTACAGGCGCTTTGAGAAGGAGAAGCTCAAGTCCCAGTGGAACAAT
Seq C2 exon
GATAATCCCCTTTTCAAGAGCGCCACCACGACGGTCATGAACCCCAAGTTTGCTGAGAGTTAGGAGCACTTGGTGAAGACAAGGCCGTCAGGACCCACCATGTCTGCCCCATCACGCGGCCGAGACATGGCTTGCCACAGCTCTTGAGGATGTCACCAATTAACCAGAAATCCAGTTATTTTCCGCCCTCAAAATGACAGCCATGGCCGGCCGGGTGCTTCTGGGGGCTCGTCGGGGGGACAGCTCCACTCTGACTGGCACAGTCTTTGCATGGAGACTTGAGGAGGGAGGGCTTGAGGTTGGTGAGGTTAGGTGCGTGTTTCCTGTGCAAGTCAGGACATCAGTCTGATTAAAGGTGGTGCCAATTTATTTACATTTAAACTTGTCAGGGTATAAAATGACATCCCATTAATTATATTGTTAATCAATCACGTGTATAGAAAAAAAATAAAACTTCAATACAGGCTGTCCATGGAAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000160255-'54-69,'54-67,58-69=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF079657=Integrin_B_tail=FE(86.1=100)
A:
PF079657=Integrin_B_tail=PD(7.6=10.7),PF087256=Integrin_b_cyt=PU(54.3=44.6)
C2:
PF087256=Integrin_b_cyt=PD(41.3=90.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GGATGGACCGCTACCTCATCT
R:
ATGGCTGTCATTTTGAGGGCG
Band lengths:
243-410
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains