MmuEX6049373 @ mm10
Exon Skipping
Gene
ENSMUSG00000000290 | Itgb2
Description
integrin beta 2 [Source:MGI Symbol;Acc:MGI:96611]
Coordinates
chr10:77561013-77565686:+
Coord C1 exon
chr10:77561013-77561215
Coord A exon
chr10:77564638-77564804
Coord C2 exon
chr10:77565178-77565686
Length
167 bp
Sequences
Splice sites
3' ss Seq
GTTGTGTGCTTTTTCCCTAGAGT
3' ss Score
9.4
5' ss Seq
AATGTGAGT
5' ss Score
7.8
Exon sequences
Seq C1 exon
CTCTTGTGCCGAGTGCCTGAAGTTTGATAAGGGCCCTTTTGAGAAGAACTGTAGTGTTCAGTGTGCTGGTATGACGCTGCAGACTATCCCTTTGAAGAAAAAGCCCTGCAAGGAGAGGGACTCGGAAGGCTGTTGGATAACTTACACTTTGCAGCAGAAGGACGGAAGGAACATTTACAACATCCATGTGGAGGACAGTCTAG
Seq A exon
AGTGTGTGAAGGGCCCCAATGTGGCTGCCATCGTAGGGGGCACCGTGGTAGGTGTCGTACTGATTGGTGTCCTCCTCCTGGTCATCTGGAAGGCCCTGACCCACCTGACTGACCTCAGGGAGTACAGGCGCTTTGAGAAGGAGAAACTCAAGTCCCAATGGAACAAT
Seq C2 exon
GACAACCCCCTCTTCAAGAGTGCTACGACAACGGTCATGAACCCCAAGTTTGCTGAAAGCTAGAGCATGAGTTATCATAATCAAGCAGATGTGACCCCCTCAGACCACGCCTCCTCCCCTCTGCAAACACAACGTGGCTTACAGCTCACCCCAGTGCTGCCAAGGATCCAAAAGCCTGCTCGGTTTCTTTCCGCCATTATATCAAGTCTGCCAGGGTTTCCAGGGACTTGTCTTCCGACCTGCACAATCTTGCCGCAGAGCCCTAAGAATTGTCCCGAGTCCCAAGAGGTTCCACCCACATTTTCTTGCATAAAGGAAGACAGCAGTCTCAGTAAAGGTGGCCCCAACTTATTTATATTTAAACTTGTCAGAGTATAAAACTCCTATTATATTGTTAACATCCCATCTGTTGTATTATATGTGAGTATAAAAACTATATCCAACGTATTATTTCATAATCATGTATGAAAAATAATAAAGCTTCCATCCATGCTGTCCAT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000000290-'35-29,'35-27,38-29
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (No Ref, Alt. Stop)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF079657=Integrin_B_tail=FE(85.0=100)
A:
PF079657=Integrin_B_tail=PD(7.5=10.7),PF087256=Integrin_b_cyt=PU(54.3=44.6)
C2:
PF087256=Integrin_b_cyt=PD(41.3=90.5)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CAGCAGAAGGACGGAAGGAAC
R:
GGAAAGAAACCGAGCAGGCTT
Band lengths:
244-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types