HsaEX6015723 @ hg38
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
LDL receptor related protein 1B [Source:HGNC Symbol;Acc:HGNC:6693]
Coordinates
chr2:141062051-141229440:-
Coord C1 exon
chr2:141229183-141229440
Coord A exon
chr2:141188421-141188583
Coord C2 exon
chr2:141062051-141062273
Length
163 bp
Sequences
Splice sites
3' ss Seq
TTTGTGTATGTGTTTTTCAGATG
3' ss Score
10.58
5' ss Seq
AGGGTAAGA
5' ss Score
9.21
Exon sequences
Seq C1 exon
AACCTACAGATAGACCACCTATACTATTAATTGCAAATTTTGAAACAATTGAGGTTTTCTATCTTAATGGAAGTAAAATGGCAACTCTAAGCTCAGTCAATGGAAATGAAATTCATACTCTGGATTTTATTTATAATGAAGATATGATTTGTTGGATTGAATCAAGAGAATCTTCAAATCAACTCAAATGTATCCAGATAACAAAAGCAGGAGGATTAACAGATGAATGGACAATCAATATTCTTCAATCCTTCCACA
Seq A exon
ATGTGCAACAAATGGCGATTGACTGGCTCACTCGAAATCTCTATTTTGTGGACCATGTCGGTGACCGGATCTTTGTTTGTAATTCCAACGGTTCTGTATGTGTCACCCTGATTGATCTGGAGCTTCACAATCCTAAAGCAATAGCAGTAGATCCAATAGCAGG
Seq C2 exon
AAAACTTTTCTTTACTGACTACGGGAATGTCGCCAAAGTGGAGAGATGTGACATGGATGGGATGAACCGAACAAGGATAATTGATTCAAAGACAGAGCAGCCAGCTGCACTGGCACTAGACCTAGTCAACAAATTGGTTTACTGGGTAGATCTTTACTTGGACTATGTGGGAGTAGTGGACTATCAAGGAAAAAATAGACACACTGTCATTCAAGGCAGACAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'15-41,'15-33,17-41
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0005812=Ldl_recept_b=WD(100=74.5),PF0005812=Ldl_recept_b=PU(0.1=0.0)
C2:
PF0005812=Ldl_recept_b=WD(100=56.0),PF0005812=Ldl_recept_b=PU(71.4=40.0)
Main Skipping Isoform:
ENST00000389484fB19030
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCAACTCTAAGCTCAGTCA
R:
CGGTTCATCCCATCCATGTCA
Band lengths:
249-412
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains