HsaEX6015736 @ hg19
Exon Skipping
Gene
ENSG00000168702 | LRP1B
Description
low density lipoprotein receptor-related protein 1B [Source:HGNC Symbol;Acc:6693]
Coordinates
chr2:141609221-141625832:-
Coord C1 exon
chr2:141625668-141625832
Coord A exon
chr2:141625159-141625403
Coord C2 exon
chr2:141609221-141609352
Length
245 bp
Sequences
Splice sites
3' ss Seq
ATGTATTTATCTTTCTGTAGGTC
3' ss Score
10.04
5' ss Seq
AGGGTAAGT
5' ss Score
10.45
Exon sequences
Seq C1 exon
AATTCTTTTCTGGACAGACTGGGATGCAAATTTTCCTCGCATTGAATCTGCCTCTATGAGTGGTGCTGGGAGAAAAACCATCTATAAAGACATGAAAACTGGGGCTTGGCCTAATGGACTAACTGTGGACCACTTTGAGAAAAGGATAGTGTGGACAGACGCCAG
Seq A exon
GTCAGATGCTATTTATTCAGCCCTCTATGATGGAACAAACATGATAGAAATCATCCGAGGTCATGAATACCTTTCCCATCCCTTTGCTGTGTCTCTATATGGGAGTGAAGTCTACTGGACAGACTGGAGGACCAACACATTGTCCAAAGCCAATAAGTGGACAGGGCAGAATGTCAGTGTGATTCAGAAAACCAGTGCACAGCCATTTGACCTTCAGATATACCATCCCAGTCGCCAGCCACAGG
Seq C2 exon
CTCCCAATCCTTGTGCAGCTAATGATGGCAAAGGCCCCTGCTCTCACATGTGTCTAATCAATCACAATAGGAGTGCTGCCTGTGCGTGCCCCCACTTGATGAAGCTTTCTTCAGACAAGAAGACCTGCTATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000168702-'26-27,'26-26,27-27=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.024 C2=0.156
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=80.4)
A:
NO
C2:
PF146701=FXa_inhibition=WD(100=86.7)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTTCTGGACAGACTGGGATGC
R:
CATAGCAGGTCTTCTTGTCTGA
Band lengths:
292-537
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)