MmuEX6101034 @ mm10
Exon Skipping
Gene
ENSMUSG00000049252 | Lrp1b
Description
low density lipoprotein-related protein 1B (deleted in tumors) [Source:MGI Symbol;Acc:MGI:2151136]
Coordinates
chr2:41284095-41296160:-
Coord C1 exon
chr2:41295996-41296160
Coord A exon
chr2:41295465-41295709
Coord C2 exon
chr2:41284095-41284226
Length
245 bp
Sequences
Splice sites
3' ss Seq
ATGTACTAACCTTTCTTTAGGTC
3' ss Score
8.84
5' ss Seq
AAGGTAGGT
5' ss Score
10.29
Exon sequences
Seq C1 exon
AATTCTTTTCTGGACAGACTGGGATGCCAATTTCCCTCGCATTGAATCTGCTTCAATGAGTGGTGCCGGAAGAAAAACCATCTATAAAGACATGAAAACTGGGGCATGGCCTAATGGACTGACCGTGGACCACTTTGAAAGAAGAATAGTTTGGACGGATGCCAG
Seq A exon
GTCAGATGCTATTTATTCAGCTTTCTATGATGGAACAAACATGATAGAAATTATCCGAGGACACGAGTACCTGTCACATCCCTTTGCTGTGTCTTTGTATGGGAGTGAGGTGTACTGGACTGATTGGAGGACCAACACACTGGCTAAAGCCAACAAGTGGACAGGGCAGAATGTCAGTGTGATCCAGAAGACGAGTGCACAACCATTCGACCTTCAGATTTACCATCCCAGTAGACAGCCACAAG
Seq C2 exon
CTCCCAACCCTTGTGCAGCCAATGAAGGTAGAGGCCCCTGCTCTCACCTGTGCCTCATCAATCATAATAGGAGTGCAGCTTGTGCCTGCCCCCACCTAATGAAGCTTTCCTCTGACAAGAAAACCTGCTATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000049252-'47-43,'47-41,48-43=AN
Average complexity
A_C3
Mappability confidence:
NA
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.024 C2=0.156
Domain overlap (PFAM):
C1:
PF0005812=Ldl_recept_b=WD(100=80.4)
A:
NO
C2:
PF146701=FXa_inhibition=WD(100=86.7)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTCTTTCCTTCTTTCTTCCTTCCT
R:
AACTGTCTCTAGTCCCGTCCC
Band lengths:
292-537
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types