HsaEX6015801 @ hg19
Exon Skipping
Gene
ENSG00000115919 | KYNU
Description
kynureninase [Source:HGNC Symbol;Acc:6469]
Coordinates
chr2:143676178-143712440:+
Coord C1 exon
chr2:143676178-143676298
Coord A exon
chr2:143685228-143685310
Coord C2 exon
chr2:143712379-143712440
Length
83 bp
Sequences
Splice sites
3' ss Seq
ATGTCCGTTTTCAATTTCAGAGC
3' ss Score
11.16
5' ss Seq
TAGGTAAGT
5' ss Score
9.66
Exon sequences
Seq C1 exon
TTGATTTATCATTAGTGAATAAAGATGAAAATGCCATCTATTTCTTGGGAAATTCTCTTGGCCTTCAACCAAAAATGGTTAAAACATATCTTGAAGAAGAACTAGATAAGTGGGCCAAAAT
Seq A exon
AGCAGCCTATGGTCATGAAGTGGGGAAGCGTCCTTGGATTACAGGAGATGAGAGTATTGTAGGCCTTATGAAGGACATTGTAG
Seq C2 exon
GAGCCAATGAGAAAGAAATAGCCCTAATGAATGCTTTGACTGTAAATTTACATCTTCTAATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000115919-'8-13,'8-9,9-13=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.018
Domain overlap (PFAM):
C1:
PF0026614=Aminotran_5=PU(11.9=68.3)
A:
PF0026614=Aminotran_5=FE(11.9=100)
C2:
PF0026614=Aminotran_5=FE(5.9=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GATGAAAATGCCATCTATTTCTTGGG
R:
TTACAGTCAAAGCATTCATTAGGGCT
Band lengths:
143-226
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)