HsaEX6015819 @ hg38
Exon Skipping
Gene
ENSG00000169554 | ZEB2
Description
zinc finger E-box binding homeobox 2 [Source:HGNC Symbol;Acc:HGNC:14881]
Coordinates
chr2:144396412-144404130:-
Coord C1 exon
chr2:144403916-144404130
Coord A exon
chr2:144401199-144401307
Coord C2 exon
chr2:144396412-144396592
Length
109 bp
Sequences
Splice sites
3' ss Seq
CAGTCTTTCTCCTTTTATAGCAC
3' ss Score
8.76
5' ss Seq
GTGGTGAGT
5' ss Score
8.95
Exon sequences
Seq C1 exon
ACCTGCCACCTGGAACTCCAGATGCTTTTGCCCAACTGCTGACCTGCCCCTACTGCGACCGGGGCTACAAGCGCTTGACATCACTGAAGGAGCACATCAAGTACCGCCACGAGAAGAATGAAGAGAACTTTTCCTGCCCTCTCTGTAGCTACACGTTTGCCTACCGCACCCAGCTCGAGCGGCATATGGTGACACACAAGCCAGGGACAGATCAG
Seq A exon
CACCAAATGCTAACCCAAGGAGCAGGTAATCGCAAGTTCAAATGCACAGAGTGTGGCAAGGCCTTCAAATATAAACACCATCTGAAAGAACACCTGCGAATTCACAGTG
Seq C2 exon
GGAGAATTGCTTGATGGAGCACAAGACTACATGTCAGGCCTAGATGATATGACAGACTCCGACTCCTGTCTGTCTCGCAAAAAGATCAAGAAGACAGAGAGTGGCATGTATGCATGTGACTTATGTGACAAGACATTCCAGAAAAGCAGTTCCCTTCTGCGACATAAATACGAACACACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000169554_MULTIEX1-1/5=C1-3
Average complexity
C2
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.265 A=0.197 C2=0.114
Domain overlap (PFAM):
C1:
PF056057=zf-Di19=PU(96.8=83.3)
A:
PF056057=zf-Di19=PD(0.1=0.0),PF134651=zf-H2C2_2=PU(38.5=27.0)
C2:
PF086465=Rep_fac-A_C=PU(85.2=90.2),PF139121=zf-C2H2_6=WD(100=49.0)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TTTGCCCAACTGCTGACCTG
R:
ACAGGAGTCGGAGTCTGTCAT
Band lengths:
258-367
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains