HsaEX6015830 @ hg19
Exon Skipping
Gene
ENSG00000204406 | MBD5
Description
methyl-CpG binding domain protein 5 [Source:HGNC Symbol;Acc:20444]
Coordinates
chr2:149246955-149267704:+
Coord C1 exon
chr2:149246955-149248163
Coord A exon
chr2:149260005-149260078
Coord C2 exon
chr2:149267629-149267704
Length
74 bp
Sequences
Splice sites
3' ss Seq
GTCTTCATACCTTCACTCAGGTG
3' ss Score
7.49
5' ss Seq
AAAGTAAGC
5' ss Score
7.31
Exon sequences
Seq C1 exon
CAGGGGATAAAATTCTAGAGGAAAATTTCAGGTATAATAACTACAAAAGAACTATGATGAGTTTTAAGGAGAGACTAGAGAACACTGTGGAAAGATGTGCACACATAAATGGGAATAGACCTCGACAGAGTCGGGGATTTGGAGAGCTGCTAAGCACTGCAAAGCAAGACCTGGTCCTAGAGGAGCAGTCTCCAAGTTCCTCAAATAGTTTGGAAAATTCTCTGGTCAAAGACTACATCCATTACAATGGAGACTTTAATGCCAAAAGCGTTAATGGGTGTGTGCCTAGCCCTTCAGATGCTAAAAGCATTAGTAGTGAAGATGACCTAAGGAACCCAGACTCCCCCTCTTCAAATGAATTGATACATTATAGACCAAGGACGTTCAATGTTGGCGACTTGGTCTGGGGCCAAATCAAAGGACTGACTTCCTGGCCTGGAAAATTAGTAAGAGAAGACGACGTTCACAATTCATGTCAACAAAGCCCCGAGGAAGGGAAG
Seq A exon
GTGGAGCCCGAGAAGTTGAAGACACTAACAGAAGGTTTGGAAGCCTACAGCCGTGTCCGGAAAAGGAACAGAAA
Seq C2 exon
AAGTGGAAAGCTAAATAACCATTTAGAAGCTGCTATTCATGAGGCCATGAGTGAACTGGACAAAATGTCTGGGACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000204406-'33-37,'33-35,34-37=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.529 A=0.964 C2=1.000
Domain overlap (PFAM):
C1:
PF0085512=PWWP=PU(46.3=9.4)
A:
PF0085512=PWWP=FE(29.3=100)
C2:
PF0085512=PWWP=PD(22.0=69.2)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AATGTTGGCGACTTGGTCTGG
R:
TCCAGTTCACTCATGGCCTCA
Band lengths:
174-248
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)