MmuEX0028086 @ mm10
Exon Skipping
Gene
ENSMUSG00000036792 | Mbd5
Description
methyl-CpG binding domain protein 5 [Source:MGI Symbol;Acc:MGI:2138934]
Coordinates
chr2:49278581-49313725:+
Coord C1 exon
chr2:49278581-49279783
Coord A exon
chr2:49298656-49298729
Coord C2 exon
chr2:49313650-49313725
Length
74 bp
Sequences
Splice sites
3' ss Seq
GTCTTCGTACCTTCACTCAGGTG
3' ss Score
8.54
5' ss Seq
AAAGTAAGC
5' ss Score
7.31
Exon sequences
Seq C1 exon
AAGGTGATAAGATTCTGGAGGAAAATTTCAGGTATAATAATTACAAAAGAACTATGATGAGTTTTAAAGAGAGACTAGAGAGTACTGTGGAGAGATGTACACACATTAACGGAAACAGACCTCGTCAGAGTCGGGGCTTTGGAGAGCTGCTAGGCACTGCAAAACAAGACCTAGTTCTAGAGGGGCAGTCTCCGGGTTCTTCAAATAGTTTGGAAAGTTCTCTGGTCAAAGACTACATCCATTACAATGGAGACTTTAATGCCAAAACCATTAATGGGTGTGTGCCTAGTCCCTCAGATGCTAAAAGCATTAGTAGTGAAGACGACCTACGGAATCCAGACTCCCCCTCCTCACATGAGTTGATACACTATAGACCAAGGACGTTCAACGTTGGCGACTTGGTCTGGGGCCAAATCAAAGGACTGACTTCCTGGCCTGGGAAATTCATAAGAGAAGACGACGTTCACAATTCATGCCAACAAAGCCCCGAGGAAGGGAAG
Seq A exon
GTGGAGCCCGAGAAGTTGAAGACTCTCACAGAAGGTTTAGAAGCCTACAGCCGCGTCCGGAAAAGGAGCAGAAA
Seq C2 exon
AAGTGGGAAACTAAATAACCATTTAGAAGCTGCTATTCACGAGGCCATGAGCGAACTGGACAAAATGTCTGGGACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000036792_MULTIEX2-3/3=1-C2
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.482 A=0.884 C2=1.000
Domain overlap (PFAM):
C1:
PF0085512=PWWP=PU(46.3=9.5)
A:
PF0085512=PWWP=FE(29.3=100)
C2:
PF0085512=PWWP=PD(22.0=69.2)
Main Skipping Isoform:
ENSMUST00000112754fB2384
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CTTGGTCTGGGGCCAAATCAA
R:
TTTGTCCAGTTCGCTCATGGC
Band lengths:
167-241
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Ribosome-engaged transcriptomes of neuronal types
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types