HsaEX6016766 @ hg19
Exon Skipping
Gene
ENSG00000091428 | RAPGEF4
Description
Rap guanine nucleotide exchange factor (GEF) 4 [Source:HGNC Symbol;Acc:16626]
Coordinates
chr2:173825850-173832172:+
Coord C1 exon
chr2:173825850-173825956
Coord A exon
chr2:173830290-173830411
Coord C2 exon
chr2:173831989-173832172
Length
122 bp
Sequences
Splice sites
3' ss Seq
TCTGTCTCACCTCTCCTTAGACA
3' ss Score
9.26
5' ss Seq
ACGGTAAGA
5' ss Score
10.65
Exon sequences
Seq C1 exon
GTCCCTTCAGAGAAGATCCTCAGAGCTGGAAAAATTTTACGAAATGCCATTCTCTCTCGAGCACCTCACATGATAAGAGATAGAAAATACCACCTAAAGACATACAG
Seq A exon
ACAATGCTGTGTGGGAACTGAACTGGTGGACTGGATGATGCAGCAGACACCATGTGTTCACTCCCGGACTCAAGCTGTTGGCATGTGGCAAGTCCTGTTAGAAGATGGTGTTCTCAACCACG
Seq C2 exon
TGGACCAGGAGCACCATTTCCAAGACAAATATTTATTCTATCGATTTCTGGATGATGAGCACGAGGATGCCCCTTTGCCTACTGAGGAGGAGAAGAAGGAGTGTGATGAGGAGCTCCAGGACACCATGCTGCTGCTGTCACAGATGGGCCCCGACGCCCACATGAGGATGATCCTTCGCAAACC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091428-'16-20,'16-18,18-20=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.226
Domain overlap (PFAM):
C1:
PF0061016=DEP=PU(19.7=38.9)
A:
PF0061016=DEP=FE(57.7=100)
C2:
PF0061016=DEP=PD(21.1=24.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGAAATGCCATTCTCTCTCGA
R:
GATCATCCTCATGTGGGCGTC
Band lengths:
242-364
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)