HsaEX6016767 @ hg38
Exon Skipping
Gene
ENSG00000091428 | RAPGEF4
Description
Rap guanine nucleotide exchange factor 4 [Source:HGNC Symbol;Acc:HGNC:16626]
Coordinates
chr2:172960760-172965683:+
Coord C1 exon
chr2:172960760-172960813
Coord A exon
chr2:172961122-172961228
Coord C2 exon
chr2:172965562-172965683
Length
107 bp
Sequences
Splice sites
3' ss Seq
TCCACCTGATTACAATCCAGGTC
3' ss Score
4.9
5' ss Seq
CAGGTATGT
5' ss Score
9.8
Exon sequences
Seq C1 exon
ACACCTCTCATTGAACCTCACGTTCCTCTTCGTCCTGCTAACACCATTACCAAG
Seq A exon
GTCCCTTCAGAGAAGATCCTCAGAGCTGGAAAAATTTTACGAAATGCCATTCTCTCTCGAGCACCTCACATGATAAGAGATAGAAAATACCACCTAAAGACATACAG
Seq C2 exon
ACAATGCTGTGTGGGAACTGAACTGGTGGACTGGATGATGCAGCAGACACCATGTGTTCACTCCCGGACTCAAGCTGTTGGCATGTGGCAAGTCCTGTTAGAAGATGGTGTTCTCAACCACG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000091428-'24-24,'24-21,26-24
Average complexity
C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.540 A=0.007 C2=0.000
Domain overlap (PFAM):
C1:
NO
A:
PF0061016=DEP=PU(19.7=38.9)
C2:
PF0061016=DEP=FE(57.7=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CACCTCTCATTGAACCTCACGT
R:
CGTGGTTGAGAACACCATCTTCT
Band lengths:
175-282
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains