HsaEX6024515 @ hg38
Exon Skipping
Gene
ENSG00000108984 | MAP2K6
Description
mitogen-activated protein kinase kinase 6 [Source:HGNC Symbol;Acc:HGNC:6846]
Coordinates
chr17:69520270-69523641:+
Coord C1 exon
chr17:69520270-69520386
Coord A exon
chr17:69521049-69521100
Coord C2 exon
chr17:69523514-69523641
Length
52 bp
Sequences
Splice sites
3' ss Seq
ATCTTGTGTTTCTCTTGCAGATT
3' ss Score
12.95
5' ss Seq
GAGGTAAGC
5' ss Score
9.85
Exon sequences
Seq C1 exon
GGTGATGTGTGGATCTGCATGGAGCTCATGGATACATCACTAGATAAATTCTACAAACAAGTTATTGATAAAGGCCAGACAATTCCAGAGGACATCTTAGGGAAAATAGCAGTTTCT
Seq A exon
ATTGTAAAAGCATTAGAACATTTACATAGTAAGCTGTCTGTCATTCACAGAG
Seq C2 exon
ACGTCAAGCCTTCTAATGTACTCATCAATGCTCTCGGTCAAGTGAAGATGTGCGATTTTGGAATCAGTGGCTACTTGGTGGACTCTGTTGCTAAAACAATTGATGCAGGTTGCAAACCATACATGGCC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000108984-'24-25,'24-24,25-25=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0006920=Pkinase=PD(20.2=89.5)
A:
PF0006920=Pkinase=FE(6.6=100)
C2:
PF0006920=Pkinase=FE(16.3=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal3)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
AGGCCAGACAATTCCAGAGGA
R:
ACAGAGTCCACCAAGTAGCCA
Band lengths:
134-186
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains