HsaEX6026986 @ hg38
Exon Skipping
Gene
ENSG00000100393 | EP300
Description
E1A binding protein p300 [Source:HGNC Symbol;Acc:HGNC:3373]
Coordinates
chr22:41131388-41137790:+
Coord C1 exon
chr22:41131388-41131633
Coord A exon
chr22:41135813-41135906
Coord C2 exon
chr22:41137653-41137790
Length
94 bp
Sequences
Splice sites
3' ss Seq
GTTATTTCATTTTGACTTAGGTG
3' ss Score
7.21
5' ss Seq
AAAGTAAGT
5' ss Score
9.72
Exon sequences
Seq C1 exon
CAATTTTGACTGGAGCACCCGTTGGACTTGGAAATCCTAGCTCTCTAGGGGTGGGTCAACAGTCTGCCCCCAACCTAAGCACTGTTAGTCAGATTGATCCCAGCTCCATAGAAAGAGCCTATGCAGCTCTTGGACTACCCTATCAAGTAAATCAGATGCCGACACAACCCCAGGTGCAAGCAAAGAACCAGCAGAATCAGCAGCCTGGGCAGTCTCCCCAAGGCATGCGGCCCATGAGCAACATGA
Seq A exon
GTGCTAGTCCTATGGGAGTAAATGGAGGTGTAGGAGTTCAAACGCCGAGTCTTCTTTCTGACTCAATGTTGCATTCAGCCATAAATTCTCAAAA
Seq C2 exon
CCCAATGATGAGTGAAAATGCCAGTGTGCCCTCCCTGGGTCCTATGCCAACAGCAGCTCAACCATCCACTACTGGAATTCGGAAACAGTGGCACGAAGATATTACTCAGGATCTTCGAAATCATCTTGTTCACAAACT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000100393_MULTIEX1-3/4=2-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.810 A=0.969 C2=0.894
Domain overlap (PFAM):
C1:
NO
A:
PF0217211=KIX=PU(11.6=25.0)
C2:
PF0217211=KIX=PU(25.9=44.7)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGCAAGCAAAGAACCAGCAGA
R:
TCGTGCCACTGTTTCCGAATT
Band lengths:
168-262
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains