HsaEX6036223 @ hg19
Exon Skipping
Gene
ENSG00000133056 | PIK3C2B
Description
phosphoinositide-3-kinase, class 2, beta polypeptide [Source:HGNC Symbol;Acc:8972]
Coordinates
chr1:204415084-204418424:-
Coord C1 exon
chr1:204418313-204418424
Coord A exon
chr1:204416564-204416706
Coord C2 exon
chr1:204415084-204415272
Length
143 bp
Sequences
Splice sites
3' ss Seq
TCCCTGATCTCATCCCCCAGATT
3' ss Score
10.01
5' ss Seq
CTGGTGAGA
5' ss Score
7.54
Exon sequences
Seq C1 exon
GGTCCTGACCTGTGGCCGGAAGCTTCTGGGTTTGTGGCCAGCAACACAGGAAAATCCCAGCGCCCGTTGGAGTGCACCTAATTTCCACCAGCCAGACAGTGTCATCCTGCAG
Seq A exon
ATTGACTTCCCCACCTCGGCCTTTGACATCAAGTTCACCAGCCCCCCTGGAGACAAGTTCAGCCCCCGCTATGAGTTTGGCAGCCTCCGGGAAGAAGACCAGCGCAAGCTTAAAGACATCATGCAGAAAGAGTCCTTGTACTG
Seq C2 exon
GCTCACTGATGCTGACAAGAAGCGCCTGTGGGAGAAGCGATATTACTGCCACTCGGAGGTGAGCTCGCTCCCCCTGGTGCTCGCCAGCGCCCCCAGCTGGGAGTGGGCTTGCCTGCCTGACATCTATGTTCTCCTGAAGCAGTGGACCCACATGAACCACCAGGATGCCCTGGGGCTCCTGCATGCCAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000133056-'25-26,'25-24,27-26=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.026 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0079219=PI3K_C2=FE(26.2=100)
A:
PF0079219=PI3K_C2=PD(3.5=10.4),PF0061315=PI3Ka=PU(11.5=43.8)
C2:
PF0061315=PI3Ka=FE(34.4=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGGCCAGCAACACAGGAAAAT
R:
CATCCTGGTGGTTCATGTGGG
Band lengths:
245-388
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)