MmuEX0035127 @ mm9
Exon Skipping
Gene
ENSMUSG00000026447 | Pik3c2b
Description
phosphoinositide-3-kinase, class 2, beta polypeptide [Source:MGI Symbol;Acc:MGI:2685045]
Coordinates
chr1:134982078-134984953:+
Coord C1 exon
chr1:134982078-134982189
Coord A exon
chr1:134983514-134983656
Coord C2 exon
chr1:134984765-134984953
Length
143 bp
Sequences
Splice sites
3' ss Seq
GTCTCTGATCCTATCCCAAGATT
3' ss Score
6.17
5' ss Seq
CTGGTGAGG
5' ss Score
8.3
Exon sequences
Seq C1 exon
AGTCTTGACCTGTGGTCGAAAGCTCCTGGGCTTGTGGCCAGCGACACAGGAAAACTCCGGTGCCCGCTGGAGTGCGCCTAATTTCCACCAGCCAGACAGTGTTATCCTGCAG
Seq A exon
ATTGACTTCCCCAGCTCGGCCTTTGACATCAAGTTCACCAGCCCCCCTGGAGACAAGTTCAGCCCCCGCTATGAGTTTGGCAGTCTCCGGGAGGAGGACCAGCGCAAACTTAAAGACATTACGCAGAAGGAGTCCCTATACTG
Seq C2 exon
GCTCACGGATGCTGACAAGAAGCAGCTGTGGGAGAAACGCTATTACTGCCACACTGAGGTGAGCTCACTCCCCCTGGTTCTCGCCAGTGCACCCAGCTGGGAGTGGGCTTGCCTGCCGGACATCTATGCTCTCCTGCAACAGTGGACTCACATGAACCACCAAGATGCCCTGGGACTCCTGCATGCCAC
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000026447_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.026 A=0.052 C2=0.000
Domain overlap (PFAM):
C1:
PF0079219=PI3K_C2=FE(26.2=100)
A:
PF0079219=PI3K_C2=PD(3.5=10.4),PF0061315=PI3Ka=PU(11.5=43.8)
C2:
PF0061315=PI3Ka=FE(34.4=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGCGACACAGGAAAACTCC
R:
GGGCATCTTGGTGGTTCATGT
Band lengths:
245-388
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types
Other AS DBs: