HsaEX6036481 @ hg19

Exon Skipping

Gene

ENSG00000117335 | CD46

Description

CD46 molecule, complement regulatory protein [Source:HGNC Symbol;Acc:6953]

Coordinates

chr1:207958416-207968858:+

Coord C1 exon

chr1:207958416-207958451

Coord A exon

chr1:207958964-207959027

Coord C2 exon

chr1:207966864-207968858

Length

64 bp

Sequences

Splice sites

3' ss Seq

TGTTTCCTGGTTTCTTATAGTTG

3' ss Score

7.75

5' ss Seq

AGGGTAAAT

5' ss Score

5.83

Exon sequences

Seq C1 exon

ATGTTTGGGTCATTGCTGTGATTGTTATTGCCATAG

Seq A exon

TTGTTGGAGTTGCAGTAATTTGTGTTGTCCCGTACAGATATCTTCAAAGGAGGAAGAAGAAAGG

Seq C2 exon

GAAAGCAGATGGTGGAGCTGAATATGCCACTTACCAGACTAAATCAACCACTCCAGCAGAGCAGAGAGGCTGAATAGATTCCACAACCTGGTTTGCCAGTTCATCTTTTGACTCTATTAAAATCTTCAATAGTTGTTATTCTGTAGTTTCACTCTCATGAGTGCAACTGTGGCTTAGCTAATATTGCAATGTGGCTTGAATGTAGGTAGCATCCTTTGATGCTTCTTTGAAACTTGTATGAATTTGGGTATGAACAGATTGCCTGCTTTCCCTTAAATAACACTTAGATTTATTGGACCAGTCAGCACAGCATGCCTGGTTGTATTAAAGCAGGGATATGCTGTATTTTATAAAATTGGCAAAATTAGAGAAATATAGTTCACAATGAAATTATATTTTCTTTGTAAAGAAAGTGGCTTGAAATCTTTTTTGTTCAAAGATTAATGCCAACTCTTAAGATTATTCTTTCACCAACTATAGAATGTATTTTATATATCGTT

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000117335-'17-25,'17-21,18-25=AN

Average complexity

A_C1

Mappability confidence:

100%=100=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.000 A=0.000 C2=0.738

Domain overlap (PFAM):

C1:

PF0248011=Herpes_gE=FE(15.1=100),PF060117=TRP=FE(19.3=100),PF122163=m04gp34like=FE(19.0=100),PF128772=DUF3827=FE(17.2=100),PF054546=DAG1=FE(17.5=100),PF151761=LRR19-TM=FE(19.0=100),PF151021=TMEM154=FE(17.5=100),PF145751=EphA2_TM=PU(18.2=83.3),PF0200911=Rifin_STEVOR=FE(25.0=100),PF0265610=DUF202=FE(26.2=100),PF055686=ASFV_J13L=FE(19.3=100),PF126692=P12=PU(23.3=83.3)

A:

PF0248011=Herpes_gE=FE(28.8=100),PF060117=TRP=FE(36.8=100),PF122163=m04gp34like=FE(36.2=100),PF128772=DUF3827=FE(32.8=100),PF054546=DAG1=FE(33.3=100),PF151761=LRR19-TM=FE(36.2=100),PF151021=TMEM154=FE(33.3=100),PF145751=EphA2_TM=FE(38.2=100),PF0200911=Rifin_STEVOR=FE(47.7=100),PF0265610=DUF202=PD(45.2=86.4),PF055686=ASFV_J13L=FE(36.8=100),PF126692=P12=FE(48.8=100)

C2:

PF0248011=Herpes_gE=PD(24.7=72.0),PF060117=TRP=PD(31.6=72.0),PF122163=m04gp34like=PD(6.9=16.0),PF128772=DUF3827=PD(29.7=76.0),PF054546=DAG1=PD(28.6=72.0),PF151761=LRR19-TM=PD(36.2=84.0),PF151021=TMEM154=PD(30.2=76.0),PF145751=EphA2_TM=PD(40.0=88.0),PF0200911=Rifin_STEVOR=PD(11.4=20.0),PF055686=ASFV_J13L=PD(31.6=72.0),PF126692=P12=PD(23.3=40.0)

Main Inclusion Isoform:

ENSP00000313875