HsaEX6042185 @ hg19
Exon Skipping
Gene
ENSG00000118898 | PPL
Description
periplakin [Source:HGNC Symbol;Acc:9273]
Coordinates
chr16:4944468-4945717:-
Coord C1 exon
chr16:4945595-4945717
Coord A exon
chr16:4945262-4945408
Coord C2 exon
chr16:4944468-4944619
Length
147 bp
Sequences
Splice sites
3' ss Seq
CCTGACCCCGTTCTCTCCAGGAC
3' ss Score
10
5' ss Seq
CAGGTGCGT
5' ss Score
9.73
Exon sequences
Seq C1 exon
TTTCACGAAGACGTGAAGGACGCTCAGGAGCTGCTGCGCAAGGTGGACTCGGACCTGAACCAGAAGTATGGCCCTGACTTCAAGGACCGGTACCAGATTGAGCTGCTGCTGCGGGAGCTGGAT
Seq A exon
GACCAGGAGAAGGTGCTGGACAAGTATGAGGACGTGGTGCAGGGGCTGCAGAAGCGAGGCCAGCAGGTGGTGCCCCTCAAGTACCGCCGGGAGACTCCGCTCAAGCCCATCCCCGTGGAGGCACTCTGTGACTTTGAGGGGGAGCAG
Seq C2 exon
GGCCTGATCTCGCGGGGCTACAGCTACACCCTGCAGAAGAACAACGGGGAGAGCTGGGAGCTCATGGACAGCGCTGGGAACAAGCTGATTGCTCCGGCCGTGTGTTTTGTGATCCCCCCCACAGACCCTGAGGCCCTGGCTCTGGCTGACAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000118898-'9-10,'9-9,10-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.024 A=0.000 C2=0.059
Domain overlap (PFAM):
C1:
PF0043516=Spectrin=FE(50.6=100)
A:
PF0043516=Spectrin=PD(40.5=65.3)
C2:
NO
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CGTGAAGGACGCTCAGGAG
R:
CAGGGCCTCAGGGTCTGTG
Band lengths:
250-397
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)