HsaEX6042415 @ hg19

Exon Skipping

Gene

ENSG00000072864 | NDE1

Description

nudE nuclear distribution E homolog 1 (A. nidulans) [Source:HGNC Symbol;Acc:17619]

Coordinates

chr16:15761143-15781368:+

Coord C1 exon

chr16:15761143-15761296

Coord A exon

chr16:15771658-15771806

Coord C2 exon

chr16:15781232-15781368

Length

149 bp

Sequences

Splice sites

3' ss Seq

GTGTCTGTGTTGTCCTTCAGGAG

3' ss Score

10.91

5' ss Seq

GCGGTATGG

5' ss Score

7.67

Exon sequences

Seq C1 exon

GGCAGAAAATACGCAAGAGGAACTCCGAGAATTCCAGGAGGGAAGCCGAGAATATGAAGCTGAATTGGAGACGCAGCTGCAACAAATTGAAACCAGGAACAGAGACCTCCTGTCCGAAAATAACCGCCTTCGCATGGAGCTGGAAACCATCAAG

Seq A exon

GAGAAGTTTGAAGTGCAGCACTCTGAAGGCTACCGGCAGATCTCAGCCTTGGAGGATGACCTCGCGCAGACCAAAGCCATTAAAGACCAATTGCAGAAATACATCAGAGAGCTGGAGCAAGCAAATGACGACCTGGAAAGAGCCAAGCG

Seq C2 exon

CGCCACGATCATGTCTCTCGAAGACTTTGAGCAGCGCTTGAATCAGGCCATCGAAAGAAATGCCTTCCTGGAAAGTGAACTTGATGAAAAAGAGAATCTCCTGGAATCTGTTCAGAGACTGAAGGATGAAGCCAGAG

VastDB Features

Vast-tools module Information

Secondary ID

ENSG00000072864-'5-9,'5-8,7-9=AN

Average complexity

A_S

Mappability confidence:

89%=80=100%

Protein Impact

ORF disruption upon sequence exclusion

No structure available

Features

Disorder rate (Iupred):

C1=0.670 A=0.297 C2=0.394

Domain overlap (PFAM):

C1:

PF079267=TPR_MLP1_2=FE(66.2=100),PF0003816=Filament=FE(42.5=100),PF040127=PspA_IM30=FE(70.8=100),PF115593=ADIP=FE(56.0=100),PF088265=DMPK_coil=FE(91.1=100),PF058377=CENP-H=PU(52.4=82.7),PF075586=Shugoshin_N=WD(100=55.8),PF039549=Lectin_N=PU(24.6=30.8),PF093045=Cortex-I_coil=PU(5.8=5.8)

A:

PF0003816=Filament=PD(37.5=93.8),PF040127=PspA_IM30=PD(18.4=29.2),PF115593=ADIP=PD(22.7=45.8),PF088265=DMPK_coil=PD(1.8=2.1),PF058377=CENP-H=PD(48.8=83.3),PF039549=Lectin_N=PD(73.0=95.8),PF093045=Cortex-I_coil=PD(90.2=95.8),PF065827=DUF1136=WD(100=50.0)

C2:

PF077956=DUF1635=FE(31.9=100),PF0030915=Sigma54_AID=WD(100=52.2),PF048808=NUDE_C=PU(25.6=87.0)

Main Inclusion Isoform:

ENSP00000379641