HsaEX6042415 @ hg38
Exon Skipping
Gene
ENSG00000072864 | NDE1
Description
nudE neurodevelopment protein 1 [Source:HGNC Symbol;Acc:HGNC:17619]
Coordinates
chr16:15667286-15687511:+
Coord C1 exon
chr16:15667286-15667439
Coord A exon
chr16:15677801-15677949
Coord C2 exon
chr16:15687375-15687511
Length
149 bp
Sequences
Splice sites
3' ss Seq
GTGTCTGTGTTGTCCTTCAGGAG
3' ss Score
10.91
5' ss Seq
GCGGTATGG
5' ss Score
7.67
Exon sequences
Seq C1 exon
GGCAGAAAATACGCAAGAGGAACTCCGAGAATTCCAGGAGGGAAGCCGAGAATATGAAGCTGAATTGGAGACGCAGCTGCAACAAATTGAAACCAGGAACAGAGACCTCCTGTCCGAAAATAACCGCCTTCGCATGGAGCTGGAAACCATCAAG
Seq A exon
GAGAAGTTTGAAGTGCAGCACTCTGAAGGCTACCGGCAGATCTCAGCCTTGGAGGATGACCTCGCGCAGACCAAAGCCATTAAAGACCAATTGCAGAAATACATCAGAGAGCTGGAGCAAGCAAATGACGACCTGGAAAGAGCCAAGCG
Seq C2 exon
CGCCACGATCATGTCTCTCGAAGACTTTGAGCAGCGCTTGAATCAGGCCATCGAAAGAAATGCCTTCCTGGAAAGTGAACTTGATGAAAAAGAGAATCTCCTGGAATCTGTTCAGAGACTGAAGGATGAAGCCAGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000072864-'12-45,'12-40,25-45
Average complexity
C1
Mappability confidence:
100%=93=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.738 A=0.260 C2=0.570
Domain overlap (PFAM):
C1:
PF079267=TPR_MLP1_2=FE(66.2=100),PF104734=CENP-F_leu_zip=FE(56.0=100),PF040127=PspA_IM30=FE(60.7=100),PF088265=DMPK_coil=FE(91.1=100)
A:
PF040127=PspA_IM30=PD(18.4=29.2)
C2:
PF048808=NUDE_C=PU(20.5=87.2)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCAGGAGGGAAGCCGAGAATA
R:
TGGCTTCATCCTTCAGTCTCTGA
Band lengths:
255-404
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains