Special

MmuEX0031223 @ mm10

Exon Skipping

Gene
Description
nudE neurodevelopment protein 1 [Source:MGI Symbol;Acc:MGI:1914453]
Coordinates
chr16:14170338-14183612:+
Coord C1 exon
chr16:14170338-14170491
Coord A exon
chr16:14175291-14175439
Coord C2 exon
chr16:14183476-14183612
Length
149 bp
Sequences
Splice sites
3' ss Seq
ACTTCTGGTCTGTTCTGCAGGAG
3' ss Score
9.45
5' ss Seq
ACGGTAGGC
5' ss Score
8.81
Exon sequences
Seq C1 exon
GGCAGAGAATACTCAGGAAGAACTCAGAGAGTTCCAGGAAGGAAGCCGAGAATACGAAGCTGAATTGGAGGCTCAGCTGCAGCAGATTGAAACCAGGAACCGGGACCTCTTGTCAGAGAATAACCGCCTTCGCATGGAGCTGGAGTCTGTGAAG
Seq A exon
GAGAAGTTTGAGATGCAGCACTCAGAGGGTTACCGGCAGATCTCAGCCTTGGAGGATGACCTGGCGCAGACGAAAGCCATTAAAGACCAACTGCAGAAATACATTAGGGAACTGGAACAAGCCAATGATGACCTGGAAAGAGCCAAACG
Seq C2 exon
AGCCACAATCATGTCCCTGGAAGACTTTGAGCAGCGTTTGAATCAAGCCATTGAAAGAAATGCCTTCCTAGAGAGTGAGCTGGATGAGAAGGAGAATCTTCTAGAATCTGTGCAGAGGCTGAAGGATGAAGCCCGAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000022678_MULTIEX1-2/5=1-4
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact

Alternative protein isoforms (No Ref, Alt. Stop)

No structure available
Features
Disorder rate (Iupred):
  C1=0.840 A=0.492 C2=0.478
Domain overlap (PFAM):

C1:
PF079267=TPR_MLP1_2=FE(63.8=100),PF040127=PspA_IM30=FE(73.9=100),PF088265=DMPK_coil=FE(89.5=100),PF0017016=bZIP_1=PU(89.4=80.8),PF075586=Shugoshin_N=WD(100=55.8)
A:
PF088265=DMPK_coil=PD(1.8=2.0)
C2:
PF079267=TPR_MLP1_2=PD(3.8=30.0),PF040127=PspA_IM30=PD(11.6=80.0),PF088265=DMPK_coil=PD(1.8=10.0),PF0017016=bZIP_1=PD(6.4=30.0)


Main Inclusion Isoform:


Main Skipping Isoform:


Other Inclusion Isoforms:


Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Chicken
(galGal4)
HIGH PSI
Zebrafish
(danRer10)
HIGH PSI
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TCCAGGAAGGAAGCCGAGAAT
R:
CATCCTTCAGCCTCTGCACAG
Band lengths:
250-399
Functional annotations
There are 0 annotated functions for this event


GENOMIC CONTEXT[edit]

INCLUSION PATTERN[edit]


SPECIAL DATASETS

  • Pre-implantation embryo development
  • Ribosome-engaged transcriptomes of neuronal types
  • Neural differentiation time course
  • Muscular differentiation time course
  • Spermatogenesis cell types
  • Reprogramming of fibroblasts to iPSCs
  • Hematopoietic precursors and cell types