HsaEX6042677 @ hg38
Exon Skipping
Gene
ENSG00000158486 | DNAH3
Description
dynein axonemal heavy chain 3 [Source:HGNC Symbol;Acc:HGNC:2949]
Coordinates
chr16:20963284-20975415:-
Coord C1 exon
chr16:20975233-20975415
Coord A exon
chr16:20969792-20969990
Coord C2 exon
chr16:20963284-20965425
Length
199 bp
Sequences
Splice sites
3' ss Seq
TGTCCTCATGCCGCCCACAGAAC
3' ss Score
9.88
5' ss Seq
CCGGTAAGT
5' ss Score
10.91
Exon sequences
Seq C1 exon
GTAGCGGTTATGCAAAGAGAACTGACAGCTCTTCAACCTCAACTCATCCTCACCTCCGAGGAAACTGCCAAGATGATGGTGAAAATTGAAGCGGAGACGAGAGAAGCTGATGGAAAGAAACTTCTGGTGCAGGCAGATGAAAAAGAAGCCAATGTTGCTGCTGCCATTGCCCAAGGAATCAAG
Seq A exon
AACGAATGTGAGGGGGACCTAGCTGAGGCAATGCCTGCACTCGAGGCTGCACTAGCTGCTCTGGACACCCTGAACCCGGCCGACATCTCGCTGGTGAAGTCGATGCAGAACCCACCAGGCCCTGTCAAACTGGTCATGGAGAGCATCTGCATCATGAAAGGGATGAAGCCAGAGAGGAAGCCAGACCCCAGTGGCTCCG
Seq C2 exon
GTAAGATGATAGAAGATTACTGGGGGGTATCCAAAAAGATTCTTGGGGATCTGAAATTCTTGGAGAGTCTTAAGACATATGACAAAGACAACATCCCCCCACTGACCATGAAGCGGATCCGGGAAAGGTTTATCAATCACCCGGAATTCCAGCCAGCTGTCATTAAAAATGTATCGTCGGCCTGCGAGGGTCTGTGCAAGTGGGTGAGGGCCATGGAGGTGTACGATCGCGTGGCCAAGGTGGTGGCTCCCAAACGGGAGCGACTGAGGGAGGCAGAGGGGAAGCTGGCTGCACAGATGCAGAAGCTGAACCAGAAAAGAGCAGAGCTGAAGCTGGTGGTAGATCGGCTCCAGGCCCTGAATGACGACTTTGAAGAGATGAACACCAAGAAAAAGGACTTGGAGGAAAACATTGAAATCTGCTCCCAAAAGCTGGTCAGGGCAGAGAAACTGATCAGTGGTCTTGGGGGAGAGAAGGACAGATGGACCGAAGCTGCCCGA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000158486-'81-88,'81-86,82-88=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.098 A=0.224 C2=0.004
Domain overlap (PFAM):
C1:
PF127772=MT=FE(17.1=100)
A:
PF127772=MT=FE(18.8=100)
C2:
PF127772=MT=PD(59.0=29.0),PF127812=AAA_9=WD(100=32.3),PF0302810=Dynein_heavy=PU(18.4=18.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCGAGGAAACTGCCAAGATGA
R:
GATCCGCTTCATGGTCAGTGG
Band lengths:
247-446
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains