HsaEX6055136 @ hg19
Exon Skipping
Gene
ENSG00000114739 | ACVR2B
Description
activin A receptor, type IIB [Source:HGNC Symbol;Acc:174]
Coordinates
chr3:38519352-38520009:+
Coord C1 exon
chr3:38519352-38519461
Coord A exon
chr3:38519632-38519783
Coord C2 exon
chr3:38519866-38520009
Length
152 bp
Sequences
Splice sites
3' ss Seq
GGGCTCTGTGTGTCCCCCAGTCA
3' ss Score
7.43
5' ss Seq
GAGGTGAGA
5' ss Score
7.66
Exon sequences
Seq C1 exon
GCAGGAGTGTGTGGCCACTGAGGAGAACCCCCAGGTGTACTTCTGCTGCTGTGAAGGCAACTTCTGCAACGAACGCTTCACTCATTTGCCAGAGGCTGGGGGCCCGGAAG
Seq A exon
TCACGTACGAGCCACCCCCGACAGCCCCCACCCTGCTCACGGTGCTGGCCTACTCACTGCTGCCCATCGGGGGCCTTTCCCTCATCGTCCTGCTGGCCTTTTGGATGTACCGGCATCGCAAGCCCCCCTACGGTCATGTGGACATCCATGAG
Seq C2 exon
GACCCTGGGCCTCCACCACCATCCCCTCTGGTGGGCCTGAAGCCACTGCAGCTGCTGGAGATCAAGGCTCGGGGGCGCTTTGGCTGTGTCTGGAAGGCCCAGCTCATGAATGACTTTGTAGCTGTCAAGATCTTCCCACTCCAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000114739-'2-4,'2-3,3-4=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.132 A=0.196 C2=0.104
Domain overlap (PFAM):
C1:
PF0106418=Activin_recp=PD(33.0=78.9)
A:
NO
C2:
PF0006920=Pkinase=PU(11.1=66.7)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Primers PCR
Suggestions for RT-PCR validation
F:
TGTGTGGCCACTGAGGAGAA
R:
GGAGTGGGAAGATCTTGACAGC
Band lengths:
245-397
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)