HsaEX6055704 @ hg38
Exon Skipping
Gene
ENSG00000164045 | CDC25A
Description
cell division cycle 25A [Source:HGNC Symbol;Acc:HGNC:1725]
Coordinates
chr3:48180721-48183836:-
Coord C1 exon
chr3:48183800-48183836
Coord A exon
chr3:48182929-48183030
Coord C2 exon
chr3:48180721-48180840
Length
102 bp
Sequences
Splice sites
3' ss Seq
TTCCTTTTTTACTTTGATAGCAG
3' ss Score
5.42
5' ss Seq
AATGTGAGT
5' ss Score
7.8
Exon sequences
Seq C1 exon
CCTTGAAAATCCTATGAGAAGAATACATTCCCTACCT
Seq A exon
CAGAAGCTGTTGGGATGTAGTCCAGCTCTGAAGAGGAGCCATTCTGATTCTCTTGACCATGACATCTTTCAGCTCATCGACCCAGATGAGAACAAGGAAAAT
Seq C2 exon
GAAGCCTTTGAGTTTAAGAAGCCAGTAAGACCTGTATCTCGTGGCTGCCTGCACTCTCATGGACTCCAGGAGGGTAAAGATCTCTTCACACAGAGGCAGAACTCTGCCCCAGCTCGGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000164045-'8-10,'8-7,9-10=AN
Average complexity
A_C1
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.908 A=0.535 C2=0.700
Domain overlap (PFAM):
C1:
PF066178=M-inducer_phosp=FE(20.0=100)
A:
PF066178=M-inducer_phosp=FE(55.0=100),PF066178=M-inducer_phosp=PU(0.1=0.0)
C2:
PF066178=M-inducer_phosp=FE(16.0=100)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Mouse
(mm9)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTATGAGAAGAATACATTCCCTACC
R:
ATCCGAGCTGGGGCAGAG
Band lengths:
146-248
Functional annotations
There are 1 annotated functions for this event
PMID: 12411508
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, detection by mass spectrometry, inhibitor, protein kinase assay. ELM ID: ELMI003208; ELM sequence: LGCSPALK; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains