RnoEX6037865 @ rn6
Exon Skipping
Gene
ENSRNOG00000020737 | Cdc25a
Description
cell division cycle 25A [Source:RGD Symbol;Acc:621498]
Coordinates
chr8:117956855-117959490:+
Coord C1 exon
chr8:117956855-117956891
Coord A exon
chr8:117957488-117957589
Coord C2 exon
chr8:117959371-117959490
Length
102 bp
Sequences
Splice sites
3' ss Seq
TCTCTGTTTTACTTTGGCAGCAG
3' ss Score
6.63
5' ss Seq
AATGTAAGT
5' ss Score
8.62
Exon sequences
Seq C1 exon
CCTTGAAATTTCCCTGAGGAGAATAAATTGCCTACCT
Seq A exon
CAGAAGCTCTTGGGGTGTAGCCCAGCGCTAAAGAGGAGCCATTCTGATTCTCTAGACCACGACATCTTTCAACTCATTGACCAGGATGAAAATAAAGAAAAT
Seq C2 exon
GAAGCATTTGAATTTAAAAAGCCAATAAGACCTGCATCTCGTGGCTGCCTGAATGCTCACGTTCACGAGGAAAGTAAGGACCCCTTTACACACAGGCAGAATTCAGCCCCAGCTCGGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSRNOG00000020737-'5-8,'5-5,7-8=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.077 A=0.294 C2=0.750
Domain overlap (PFAM):
C1:
PF066178=M-inducer_phosp=FE(4.9=100)
A:
PF066178=M-inducer_phosp=FE(13.5=100)
C2:
PF066178=M-inducer_phosp=FE(15.9=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Mouse
(mm9)
No conservation detected
Zebrafish
(danRer10)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
CCTTGAAATTTCCCTGAGGAGA
R:
GCTGGGGCTGAATTCTGC
Band lengths:
150-252
Functional annotations
There are 1 annotated functions for this event
PMID: 12411508
Encodes an experimentally validated Eukaryotic Linear Motif (ELM). Method: alanine scanning, detection by mass spectrometry, inhibitor, protein kinase assay. ELM ID: ELMI003208; ELM sequence: LGCSPALK; Overlap: FULL
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]