HsaEX6055972 @ hg38
Exon Skipping
Gene
ENSG00000172037 | LAMB2
Description
laminin subunit beta 2 [Source:HGNC Symbol;Acc:HGNC:6487]
Coordinates
chr3:49130231-49131152:-
Coord C1 exon
chr3:49130950-49131152
Coord A exon
chr3:49130746-49130860
Coord C2 exon
chr3:49130231-49130419
Length
115 bp
Sequences
Splice sites
3' ss Seq
CTACCTGCCAACCTCTATAGGTG
3' ss Score
8.79
5' ss Seq
CCTGTAGGA
5' ss Score
-0.64
Exon sequences
Seq C1 exon
ACCTGTTGAAGATCACCAACCTACGGGTGAACCTGACTCGTCTACACACGTTGGGAGACAACCTACTCGACCCACGGAGGGAGATCCGAGAGAAGTACTACTATGCCCTCTATGAGCTGGTTGTACGTGGCAACTGCTTCTGCTACGGACACGCCTCAGAGTGTGCACCCGCCCCAGGGGCACCAGCCCATGCTGAGGGCATG
Seq A exon
GTGCACGGAGCTTGCATCTGCAAACACAACACACGTGGCCTCAACTGCGAGCAGTGTCAGGATTTCTATCGTGACCTGCCCTGGCGTCCGGCTGAGGACGGCCATAGTCATGCCT
Seq C2 exon
AGTGTGAGTGCCATGGGCACACCCACAGCTGCCACTTCGACATGGCCGTATACCTGGCATCTGGCAATGTGAGTGGAGGTGTGTGTGATGGATGTCAGCATAACACAGCTGGGCGCCACTGTGAGCTCTGTCGGCCCTTCTTCTACCGTGACCCAACCAAGGACCTGCGGGATCCGGCTGTGTGCCGCT
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000172037-'13-14,'13-13,14-14
Average complexity
S*
Mappability confidence:
100%=100=100%
Protein Impact
In the CDS, with uncertain impact
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005512=Laminin_N=PD(18.3=63.2),PF0005319=Laminin_EGF=PU(35.5=32.4)
A:
PF0005319=Laminin_EGF=PD(61.3=92.7)
C2:
PF0005319=Laminin_EGF=WD(100=95.3)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Rat
(rn6)
No conservation detected
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACTCGTCTACACACGTTGGGA
R:
ACTCACATTGCCAGATGCCAG
Band lengths:
242-357
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains