DreEX6080001 @ danRer10
Exon Skipping
Gene
ENSDARG00000002084 | lamb2
Description
laminin, beta 2 (laminin S) [Source:ZFIN;Acc:ZDB-GENE-081030-4]
Coordinates
chr23:20286970-20287663:-
Coord C1 exon
chr23:20287461-20287663
Coord A exon
chr23:20287245-20287365
Coord C2 exon
chr23:20286970-20287158
Length
121 bp
Sequences
Splice sites
3' ss Seq
TTCAGCATTTTCATTCTTAGGTT
3' ss Score
8.71
5' ss Seq
AGAGTAATT
5' ss Score
1.61
Exon sequences
Seq C1 exon
ACCAGCTGAAGATCACAAATCTTCGCCTGAATCTTACCAAGCTGCACACTCTGGGTGACAATCTGCTGGACTCACGGCCTGAGATCAAGGAGAAATACTACTATGCCATGTATGAGCTGGTCGTCAGGGGCAACTGCTTCTGCTATGGCCACGCCTCTGAGTGTGCGCCAATTGAGGGCATCAGGGATGACATTGAAGGCATG
Seq A exon
GTTCACGGGAGGTGTGTGTGCAAACACAACACTAAAGGACTGAACTGTGAACAGTGTGACGACTTCTACAATGATCTGCCCTGGAGACCAGCAGAAGGCCGGAACACTAATGCCTGCAAGA
Seq C2 exon
AATGCAACTGTAATGGTCACTCCAACCAGTGTCATTTTGACATGGCGGTGTATTTGGCAACGGGGAACATCAGTGGAGGTGTGTGTGACAACTGCCTTCACAACACCATGGGCAGCAACTGTGAGAGCTGTAAACCTTTCTACTACCAGGATCCAACTAGAGATATTAGAGACCCTGGAGTCTGTGTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSDARG00000002084-'9-11,'9-10,10-11=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF0005512=Laminin_N=PD(18.3=63.2),PF0005319=Laminin_EGF=PU(35.5=32.4)
A:
PF0005319=Laminin_EGF=PD(61.3=92.7)
C2:
PF0005319=Laminin_EGF=WD(100=95.3)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
GACAATCTGCTGGACTCACGG
R:
CCATGGTGTTGTGAAGGCAGT
Band lengths:
258-379
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]