HsaEX6063626 @ hg19
Exon Skipping
Gene
ENSG00000107290 | SETX
Description
senataxin [Source:HGNC Symbol;Acc:445]
Coordinates
chr9:135209995-135218186:-
Coord C1 exon
chr9:135218077-135218186
Coord A exon
chr9:135211683-135211902
Coord C2 exon
chr9:135209995-135210114
Length
220 bp
Sequences
Splice sites
3' ss Seq
TAAATATATTCTGCATTTAGGTT
3' ss Score
7.93
5' ss Seq
TAGGTGAGT
5' ss Score
8.83
Exon sequences
Seq C1 exon
ACGAGTTATGTGTTGAAGCACTTTGTCGGATGGAACAAGCCAATTGCTCCTTTCAGGTGTTTGATAAACATCCAGGGATCTATTTGTTTTTAGTCCATCCCAATGAAATG
Seq A exon
GTTCGGCGTTGGGCTATCTTGACTGCAAGAAACTTGGGGAAAGTGGACAGAGATGATTATTATGACTTACAAGAAGTTTTACTTTGCCTTTTTAAAGTCATTGAGTTGGGGCTTTTAGAGAGTCCAGACATTTATACTTCTTCTGTCCTAGAGAAGGGTAAACTGATTCTTCTGCCCTCACACATGTATGATACTACCAACTACAAAAGCTATTGGTTAG
Seq C2 exon
GTATTTGCATGTTGCTGACCATTCTTGAGGAACAAGCCATGGATTCCCTGTTGTTGGGCTCAGACAAACAAAATGATTTTATGCAATCGATACTTCACACTATGGAGAGGGAAGCAGATG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000107290-'7-10,'7-9,8-10=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF127262=SEN1_N=FE(13.8=100)
A:
PF127262=SEN1_N=FE(28.0=100)
C2:
PF127262=SEN1_N=FE(15.3=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACGAGTTATGTGTTGAAGCACT
R:
TCTGCTTCCCTCTCCATAGTGT
Band lengths:
228-448
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)