HsaEX6064122 @ hg38
Exon Skipping
Gene
ENSG00000159069 | FBXW5
Description
F-box and WD repeat domain containing 5 [Source:HGNC Symbol;Acc:HGNC:13613]
Coordinates
chr9:136942769-136944106:-
Coord C1 exon
chr9:136943891-136944106
Coord A exon
chr9:136943349-136943506
Coord C2 exon
chr9:136942769-136942943
Length
158 bp
Sequences
Splice sites
3' ss Seq
TGACAACTGCCCACCCGCAGCGG
3' ss Score
7.31
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
GGCCGCCTGGGCAGAATGTCACGATGGACGAGGGCGGCACGCCCCTGCTCCCCGACAGCCTGGTCTACCAGATCTTCCTGAGCCTGGGCCCGGCCGACGTGCTGGCCGCCGGGCTGGTGTGCCGCCAATGGCAGGCCGTGTCGCGGGACGAGTTCCTGTGGAGGGAGCAGTTCTACCGCTACTACCAGGTGGCCCGCGACGTGCCCCGACACCCAG
Seq A exon
CGGCCATGTCCTGGTACGAGGAGTTCCAGCGGCTGTATGACACGGTGCCCTGCGTGGAGGTGCAGACGCTGCGGGAACACACAGACCAGGTCCTGCACCTCAGCTTCTCCCATTCCGGGTACCAGTTCGCGTCCTGCTCCAAGGACTGCACTGTGAAG
Seq C2 exon
ATCTGGAGCAACGACCTGACCATCTCGCTGCTGCACAGCGCGGACATGCGGCCCTACAACTGGAGCTACACCCAGTTCTCCCAGTTCAACAAGGACGACTCGCTACTGCTGGCCTCGGGGGTGTTCCTGGGGCCGCACAACTCCTCATCCGGCGAGATTGCTGTCATCAGCCTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000159069-'2-14,'2-9,3-14
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
No structure available
Features
Disorder rate (Iupred):
C1=0.031 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF129372=F-box-like=WD(100=72.3)
A:
PF0040027=WD40=PU(89.7=66.0)
C2:
PF0040027=WD40=PD(5.1=3.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ACCAGATCTTCCTGAGCCTGG
R:
GCGAGTCGTCCTTGTTGAACT
Band lengths:
253-411
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains