MmuEX0018961 @ mm9
Exon Skipping
Gene
ENSMUSG00000015095 | Fbxw5
Description
F-box and WD-40 domain protein 5 [Source:MGI Symbol;Acc:MGI:1354731]
Coordinates
chr2:25357456-25358565:+
Coord C1 exon
chr2:25357456-25357671
Coord A exon
chr2:25357921-25358078
Coord C2 exon
chr2:25358391-25358565
Length
158 bp
Sequences
Splice sites
3' ss Seq
TGACACTATATTGCCCACAGCGG
3' ss Score
6.98
5' ss Seq
AAGGTGAGG
5' ss Score
9.16
Exon sequences
Seq C1 exon
GACCGTCTGGGCAGAATGTCACGATGGATGAGGGGGGCCTGCCCCTGCTCCCCGACAGCCTTGTCTACCAGATCTTCCTGAGTTTGGGCCCTGCAGATGTGCTGGCTGCTGGGCTGGTATGCCGCCAATGGCAGGCTGTGTCCCGGGATGAGTTCTTATGGAAGGAGCAATTCTACCGCTACTACCAGGTGGCTCGAGATGTGCCCCGCCACCCAG
Seq A exon
CGGCCACATCCTGGTATGAGGAGTTCCGGCGGCTCTATGACATGGTACCCTGTGTGGAGGTGCAGACACTGAAGGAGCACACTGACCAGGTCCTGCACCTCAGCTTCTCCCACTCGGGGTACCAGTTTGCCTCCTGCTCCAAGGACTGCACGGTGAAG
Seq C2 exon
ATCTGGAACAACGACCTGACCATCTCACTGCTGCACAGTGCAGATATGAGGCCATACAACTGGAGTTACACCCAGTTTTCCCAGTTCAACCAGGATGACTCACTGCTGCTGGCCTCAGGGGTGTTCCTGGGGCCACATAACTCCTCCTCAGGCGAGATAGCTGTCATCAGCTTAG
VastDB Features
Vast-tools module Information
Secondary ID
ENSMUSG00000015095_CASSETTE1
Average complexity
S
Mappability confidence:
100%=100=100%
Protein Impact
ORF disruption upon sequence exclusion
Show structural model
Features
Disorder rate (Iupred):
C1=0.010 A=0.000 C2=0.000
Domain overlap (PFAM):
C1:
PF129372=F-box-like=WD(100=72.3)
A:
PF0040027=WD40=PU(89.7=66.0)
C2:
PF0040027=WD40=PD(5.1=3.4)
Main Skipping Isoform:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
ATCTTCCTGAGTTTGGGCCCT
R:
CAGCAGCAGTGAGTCATCCTG
Band lengths:
256-414
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Pre-implantation embryo development
- Neural differentiation time course
- Muscular differentiation time course
- Spermatogenesis cell types
- Reprogramming of fibroblasts to iPSCs
- Hematopoietic precursors and cell types