HsaEX6064272 @ hg19
Exon Skipping
Gene
ENSG00000188986 | COBRA1
Description
cofactor of BRCA1 [Source:HGNC Symbol;Acc:24324]
Coordinates
chr9:140160329-140161538:+
Coord C1 exon
chr9:140160329-140160431
Coord A exon
chr9:140160783-140160878
Coord C2 exon
chr9:140161396-140161538
Length
96 bp
Sequences
Splice sites
3' ss Seq
TGAGCCCGTCCTCCCTACAGGAC
3' ss Score
10.78
5' ss Seq
ATGGTAACG
5' ss Score
6.05
Exon sequences
Seq C1 exon
GGACCTGTCCATGATCCTGTGTGACCCCTTCGCCATCAACACGCTGGCACTGAGCACAGTCAGGCACCTGCAGGAGCTGGTCGGCCAGGAGACACTGCCCAGG
Seq A exon
GACAGCCCCGACCTCCTGCTGCTGCTCCGGCTGCTGGCGCTGGGCCAGGGAGCCTGGGACATGATCGACAGCCAGGTCTTCAAGGAGCCCAAGATG
Seq C2 exon
GAGGTAGAGCTCATCACCAGGTTCCTCCCGATGCTCATGTCCTTCCTGGTGGATGACTACACTTTCAATGTGGATCAGAAACTTCCGGCTGAGGAGAAAGCCCCAGTCTCATATCCAAACACACTTCCCGAAAGCTTCACTAA
VastDB Features
Vast-tools module Information
Secondary ID
ENSG00000188986-'7-7,'7-6,8-7=AN
Average complexity
A_S
Mappability confidence:
100%=100=100%
Protein Impact
Alternative protein isoforms (Ref)
No structure available
Features
Disorder rate (Iupred):
C1=0.000 A=0.000 C2=0.021
Domain overlap (PFAM):
C1:
PF062098=COBRA1=FE(7.2=100)
A:
PF062098=COBRA1=FE(6.5=100)
C2:
PF062098=COBRA1=FE(9.9=100)
Main Skipping Isoform:
NA
Other Inclusion Isoforms:
NA
Other Skipping Isoforms:
NA
Associated events
Other assemblies
Conservation
Fruitfly
(dm6)
No conservation detected
Primers PCR
Suggestions for RT-PCR validation
F:
TGATCCTGTGTGACCCCTTCG
R:
GCCGGAAGTTTCTGATCCACA
Band lengths:
181-277
Functional annotations
There are 0 annotated functions for this event
GENOMIC CONTEXT[edit]
INCLUSION PATTERN[edit]
SPECIAL DATASETS
- Autistic and control brains
Other AS DBs:
FasterDB (Includes CLIP-seq data)
AS-ALPS (AS-induced ALteration of Protein Structure, links to PINs)
APPRIS (Selection of principal isoform)
DEU primates (Only for human)